Disease: Spasticity, CTCAE
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
PRNP F7VJQ1 P04156 prion protein 6.3E-04 0.445 0.923
CACNA1A O00555 calcium voltage-gated channel subunit alpha1 A Ion channel 1.00 0.489 0.769
GRIN2D O15399 glutamate ionotropic receptor NMDA type subunit 2D Ion channel 1.00 0.650 0.538
SYNJ1 O43426 synaptojanin 1 Enzyme 0.43 0.576 0.577
CACNA1G O43497 calcium voltage-gated channel subunit alpha1 G Ion channel 1.00 0.590 0.577
KIF1C O43896 kinesin family member 1C Cellular structure 0.72 0.700 0.500
PLA2G6 O60733 phospholipase A2 group VI Enzyme modulator 2.5E-10 0.476 0.846
HCN1 O60741 hyperpolarization activated cyclic nucleotide gated potassium channel 1 1.00 0.564 0.654
ACTL6B O94805 actin like 6B Cellular structure 2.8E-04 0.656 0.462
SOD1 P00441 superoxide dismutase 1 Enzyme 0.18 0.379 0.962
ATXN8OS P0DMR3 ATXN8 opposite strand lncRNA 0.650 0.423
KCNA2 P16389 potassium voltage-gated channel subfamily A member 2 Ion channel 0.91 0.612 0.577
GABRG2 P18507 gamma-aminobutyric acid type A receptor subunit gamma2 Ion channel 0.74 0.548 0.654
PEX2 P28328 peroxisomal biogenesis factor 2 2.6E-04 0.582 0.654
L1CAM P32004 L1 cell adhesion molecule 1.00 0.475 0.769
ATP6V1A P38606 ATPase H+ transporting V1 subunit A Transporter 0.87 0.579 0.615
HTT P42858 huntingtin 1.00 0.548 0.654
SLC1A2 P43004 solute carrier family 1 member 2 Transporter 0.71 0.511 0.731
MATR3 P43243 matrin 3 1.00 0.631 0.538
GABRB2 P47870 gamma-aminobutyric acid type A receptor subunit beta2 Ion channel 0.85 0.619 0.500
DHPS P49366 deoxyhypusine synthase 1.6E-04 0.670 0.538
AARS1 P49588 alanyl-tRNA synthetase 1 Nucleic acid binding 1.8E-08 0.647 0.462
EIF2B2 P49770 eukaryotic translation initiation factor 2B subunit beta 2.1E-10 0.647 0.538
ALDH18A1 P54886 aldehyde dehydrogenase 18 family member A1 Enzyme 8.1E-04 0.551 0.769
TPI1 P60174 triosephosphate isomerase 1 Enzyme 3.0E-02 0.517 0.846