Disease: Hyperalgesia, Thermal
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
IL6 P05231 interleukin 6 0.32 0.248 0.962
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962
IL10 P22301 interleukin 10 5.9E-03 0.281 0.923
PTGS2 P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1.00 0.314 0.962
CCL2 P13500 C-C motif chemokine ligand 2 Signaling 0.61 0.321 0.962
TLR4 O00206 toll like receptor 4 4.6E-09 0.321 0.962
MAPK1 P28482 mitogen-activated protein kinase 1 Kinase 1.00 0.330 0.923
IL4 P05112 interleukin 4 4.7E-03 0.332 0.962
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923
NOS2 P35228 nitric oxide synthase 2 4.0E-15 0.364 0.923
AGT P01019 angiotensinogen Enzyme modulator 5.0E-08 0.367 0.923
HMGB1 P09429 high mobility group box 1 Nucleic acid binding 0.82 0.368 0.923
IL1RN P18510 interleukin 1 receptor antagonist 3.1E-02 0.373 0.923
SIRT1 Q96EB6 sirtuin 1 Epigenetic regulator 8.7E-02 0.378 0.885
MAPK3 P27361 mitogen-activated protein kinase 3 Kinase 3.7E-02 0.379 0.885
NGF P01138 nerve growth factor Signaling 0.82 0.391 0.885
GJA1 P17302 gap junction protein alpha 1 Cell-cell junction 0.16 0.393 0.885
COMT P21964 catechol-O-methyltransferase Enzyme 1.1E-06 0.400 0.923
FOS P01100 Fos proto-oncogene, AP-1 transcription factor subunit Transcription factor 0.26 0.411 0.885
CALCA P01258 P06881 calcitonin related polypeptide alpha Signaling 1.6E-02 0.416 0.923
TAC1 P20366 tachykinin precursor 1 0.75 0.424 0.923
S100A9 P06702 S100 calcium binding protein A9 Calcium-binding protein 0.48 0.433 0.885
DNMT3A Q9Y6K1 DNA methyltransferase 3 alpha 7.4E-39 0.445 0.846
CNR1 P21554 cannabinoid receptor 1 G-protein coupled receptor 0.51 0.446 0.808