Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
MIR451A microRNA 451a 0.505 0.769
DNMT3A Q9Y6K1 DNA methyltransferase 3 alpha 7.4E-39 0.445 0.846
TRPA1 O75762 transient receptor potential cation channel subfamily A member 1 Ion channel 7.2E-35 0.546 0.846
TRPM8 Q7Z2W7 transient receptor potential cation channel subfamily M member 8 Ion channel 4.6E-29 0.553 0.808
TRPV1 Q8NER1 transient receptor potential cation channel subfamily V member 1 Ion channel 1.0E-16 0.446 0.885
TRPV4 Q9HBA0 transient receptor potential cation channel subfamily V member 4 Ion channel 2.2E-16 0.457 0.808
NOS2 P35228 nitric oxide synthase 2 4.0E-15 0.364 0.923
P2RX2 Q9UBL9 purinergic receptor P2X 2 Ion channel 9.7E-13 0.585 0.769
P2RX4 Q99571 purinergic receptor P2X 4 Ion channel 5.0E-12 0.547 0.808
P2RX7 Q99572 purinergic receptor P2X 7 Ion channel 3.3E-11 0.450 0.808
OPRM1 P35372 opioid receptor mu 1 G-protein coupled receptor 7.9E-11 0.457 0.808
MC1R Q01726 melanocortin 1 receptor G-protein coupled receptor 8.1E-11 0.524 0.808
KNG1 P01042 kininogen 1 Enzyme modulator 3.2E-10 0.481 0.885
TLR4 O00206 toll like receptor 4 4.6E-09 0.321 0.962
AGT P01019 angiotensinogen Enzyme modulator 5.0E-08 0.367 0.923
ASIC3 Q9UHC3 acid sensing ion channel subunit 3 Ion channel 3.4E-07 0.663 0.538
P2RX3 P56373 purinergic receptor P2X 3 Ion channel 1.0E-06 0.565 0.769
COMT P21964 catechol-O-methyltransferase Enzyme 1.1E-06 0.400 0.923
AIF1 P55008 allograft inflammatory factor 1 Calcium-binding protein 1.9E-06 0.521 0.808
CCKBR P32239 cholecystokinin B receptor G-protein coupled receptor 2.1E-06 0.573 0.615
CNR2 P34972 cannabinoid receptor 2 G-protein coupled receptor 6.5E-06 0.509 0.846
HCN3 Q9P1Z3 hyperpolarization activated cyclic nucleotide gated potassium channel 3 Ion channel 2.6E-05 0.792 0.308
F2RL1 P55085 F2R like trypsin receptor 1 G-protein coupled receptor 1.5E-04 0.480 0.769
P2RY12 Q9H244 purinergic receptor P2Y12 G-protein coupled receptor 1.7E-03 0.533 0.731
BDKRB1 P46663 bradykinin receptor B1 G-protein coupled receptor 4.7E-03 0.619 0.731