Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
SPG7 Q9UQ90 SPG7 matrix AAA peptidase subunit, paraplegin Enzyme 2.0E-36 0.436 0.885
PSEN1 P49768 presenilin 1 Enzyme 0.97 0.469 0.846
NTRK2 Q16620 neurotrophic receptor tyrosine kinase 2 Kinase 1.00 0.479 0.808
UCHL1 P09936 ubiquitin C-terminal hydrolase L1 Enzyme 0.99 0.482 0.885
TIMM8A O60220 translocase of inner mitochondrial membrane 8A 0.65 0.510 0.846
HTT P42858 huntingtin 1.00 0.548 0.654
KIF1A Q12756 kinesin family member 1A Cellular structure 1.00 0.559 0.692
ATP6AP2 O75787 ATPase H+ transporting accessory protein 2 Receptor 0.87 0.525 0.769
CAPN1 P07384 calpain 1 Enzyme 5.9E-10 0.539 0.808
STUB1 Q9UNE7 STIP1 homology and U-box containing protein 1 1.9E-02 0.544 0.692
ABCD1 P33897 ATP binding cassette subfamily D member 1 Transporter 1.00 0.563 0.731
CYP7B1 O75881 cytochrome P450 family 7 subfamily B member 1 Enzyme 3.3E-06 0.563 0.692
SPG11 Q96JI7 SPG11 vesicle trafficking associated, spatacsin 1.6E-39 0.576 0.538
SPAST Q9UBP0 spastin Cellular structure 1.00 0.579 0.577
FA2H Q7L5A8 fatty acid 2-hydroxylase Enzyme 0.15 0.573 0.654
RAB18 Q9NP72 RAB18, member RAS oncogene family 0.91 0.582 0.692
KIF5A Q12840 kinesin family member 5A Cellular structure 1.00 0.593 0.731
ATL1 Q8WXF7 atlastin GTPase 1 Enzyme modulator 0.98 0.593 0.654
SPART Q8N0X7 spartin 3.0E-07 0.588 0.654
ADGRG1 Q9Y653 adhesion G protein-coupled receptor G1 G-protein coupled receptor 5.3E-10 0.590 0.654
SLC52A3 Q9NQ40 solute carrier family 52 member 3 Transporter 1.9E-02 0.610 0.654
ERLIN2 O94905 ER lipid raft associated 2 6.7E-04 0.647 0.500
REEP1 Q9H902 receptor accessory protein 1 Transporter 0.99 0.653 0.423
PIGT Q969N2 phosphatidylinositol glycan anchor biosynthesis class T 7.3E-10 0.633 0.615
GBA2 Q9HCG7 glucosylceramidase beta 2 2.0E-20 0.636 0.654