Disease: Frontotemporal Lobar Degeneration
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
GFRA2 O00451 GDNF family receptor alpha 2 9.8E-02 0.716 0.423
TMEM106B Q9NUM4 transmembrane protein 106B 0.33 0.590 0.462
DCTN1 Q14203 dynactin subunit 1 Chaperone 8.4E-02 0.597 0.500
TOMM40 O96008 translocase of outer mitochondrial membrane 40 Transporter 0.99 0.590 0.538
SNCB Q16143 synuclein beta Transporter 6.8E-02 0.619 0.577
SNCG O76070 synuclein gamma Transporter 8.5E-04 0.550 0.615
PNO1 Q9NRX1 partner of NOB1 homolog 0.23 0.564 0.615
MAK16 Q9BXY0 MAK16 homolog 0.96 0.566 0.615
HTT P42858 huntingtin 1.00 0.548 0.654
PSEN2 P49810 presenilin 2 Enzyme 5.4E-04 0.550 0.654
NPC1 O15118 NPC intracellular cholesterol transporter 1 Transporter 6.5E-06 0.518 0.692
SRRM2 Q9UQ35 serine/arginine repetitive matrix 2 1.00 0.564 0.692
RBMS3 Q6XE24 RNA binding motif single stranded interacting protein 3 0.21 0.553 0.692
CHMP2B Q9UQN3 charged multivesicular body protein 2B 4.6E-06 0.543 0.731
NEFL P07196 neurofilament light 0.488 0.769
PTBP1 P26599 polypyrimidine tract binding protein 1 1.00 0.517 0.769
TREM2 Q9NZC2 triggering receptor expressed on myeloid cells 2 3.3E-09 0.519 0.769
C9orf72 Q96LT7 C9orf72-SMCR8 complex subunit 1.1E-06 0.496 0.769
RUNX1T1 Q06455 RUNX1 partner transcriptional co-repressor 1 Transcription factor 0.98 0.530 0.808
CDR1 P51861 cerebellar degeneration related protein 1 0.576 0.808
CST3 P01034 cystatin C 3.9E-03 0.436 0.808
HCRT O43612 hypocretin neuropeptide precursor 2.9E-02 0.500 0.808
ATXN2 Q99700 ataxin 2 Nucleic acid binding 0.85 0.482 0.808
SLC6A4 P31645 solute carrier family 6 member 4 Transporter 0.25 0.429 0.808
SYP P08247 synaptophysin Transporter 0.92 0.481 0.808