Disease: Frontotemporal Lobar Degeneration
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
PRNP F7VJQ1 P04156 prion protein 6.3E-04 0.445 0.923
GFRA2 O00451 GDNF family receptor alpha 2 9.8E-02 0.716 0.423
NPC1 O15118 NPC intracellular cholesterol transporter 1 Transporter 6.5E-06 0.518 0.692
HCRT O43612 hypocretin neuropeptide precursor 2.9E-02 0.500 0.808
SNCG O76070 synuclein gamma Transporter 8.5E-04 0.550 0.615
TOMM40 O96008 translocase of outer mitochondrial membrane 40 Transporter 0.99 0.590 0.538
SOD1 P00441 superoxide dismutase 1 Enzyme 0.18 0.379 0.962
CP P00450 ceruloplasmin Enzyme 4.2E-10 0.466 0.846
CST3 P01034 cystatin C 3.9E-03 0.436 0.808
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962
CSF2 P04141 colony stimulating factor 2 Signaling 0.83 0.330 0.962
SOD2 P04179 superoxide dismutase 2 Enzyme 0.15 0.379 0.923
APP P05067 amyloid beta precursor protein Enzyme modulator 4.7E-02 0.422 0.846
IL6 P05231 interleukin 6 0.32 0.248 0.962
NEFL P07196 neurofilament light 0.488 0.769
SYP P08247 synaptophysin Transporter 0.92 0.481 0.808
MAPT P10636 microtubule associated protein tau 6.0E-03 0.446 0.923
CCL2 P13500 C-C motif chemokine ligand 2 Signaling 0.61 0.321 0.962
GFAP P14136 glial fibrillary acidic protein 1.5E-06 0.421 0.885
AKR1C4 P17516 aldo-keto reductase family 1 member C4 Enzyme 2.2E-17 0.587 0.846
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923
PTBP1 P26599 polypyrimidine tract binding protein 1 1.00 0.517 0.769
GRN P28799 granulin precursor 7.0E-02 0.435 0.846
NOS3 P29474 nitric oxide synthase 3 6.7E-07 0.378 0.885