| Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
|---|---|---|---|---|---|---|
| ABCB1 | P08183 | ATP binding cassette subfamily B member 1 | Transporter | 1.3E-05 | 0.344 | 0.885 |
| ANGPT2 | O15123 | angiopoietin 2 | Signaling | 0.83 | 0.410 | 0.846 |
| BCL2 | P10415 | BCL2 apoptosis regulator | Signaling | 0.56 | 0.291 | 0.885 |
| CASP3 | P42574 | caspase 3 | Enzyme | 0.10 | 0.351 | 0.923 |
| CCND1 | P24385 | cyclin D1 | Enzyme modulator | 0.89 | 0.344 | 0.923 |
| CDKN2A | P42771 Q8N726 | cyclin dependent kinase inhibitor 2A | 0.39 | 0.300 | 0.885 | |
| CDKN2B | P42772 | cyclin dependent kinase inhibitor 2B | 7.3E-03 | 0.417 | 0.769 | |
| DPYD | Q12882 | dihydropyrimidine dehydrogenase | Enzyme | 3.4E-22 | 0.493 | 0.846 |
| EGFR | P00533 | epidermal growth factor receptor | Kinase | 0.37 | 0.295 | 0.885 |
| GDNF | P39905 | glial cell derived neurotrophic factor | Signaling | 0.20 | 0.434 | 0.885 |
| HTC2 | hypertrichosis 2 (generalized, congenital) | 0.392 | 0.808 | |||
| IDH1 | O75874 | isocitrate dehydrogenase (NADP(+)) 1 | 2.6E-12 | 0.424 | 0.808 | |
| KIT | P10721 | KIT proto-oncogene, receptor tyrosine kinase | Kinase | 0.98 | 0.366 | 0.808 |
| LIG4 | P49917 | DNA ligase 4 | 4.2E-06 | 0.478 | 0.846 | |
| MGMT | P16455 | O-6-methylguanine-DNA methyltransferase | 1.2E-07 | 0.412 | 0.885 | |
| NOS2 | P35228 | nitric oxide synthase 2 | 4.0E-15 | 0.364 | 0.923 | |
| PIK3CA | P42336 | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | Kinase | 1.00 | 0.292 | 0.923 |
| PTEN | P60484 | phosphatase and tensin homolog | Enzyme | 0.26 | 0.305 | 0.923 |
| SOX2 | P48431 | SRY-box transcription factor 2 | Transcription factor | 0.71 | 0.405 | 0.808 |
| TCF12 | Q99081 | transcription factor 12 | Transcription factor | 0.68 | 0.565 | 0.654 |
| TP53 | P04637 | tumor protein p53 | Transcription factor | 0.53 | 0.236 | 0.962 |
| VEGFA | P15692 | vascular endothelial growth factor A | Signaling | 2.4E-05 | 0.266 | 0.923 |