Disease: Alzheimer disease, familial, type 3
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
IFNA1 P01562 interferon alpha 1 0.371 0.923
IFNA13 P01562 interferon alpha 13 0.374 0.923
NEFL P07196 neurofilament light 0.488 0.769
MIR181C microRNA 181c 0.555 0.769
LRRK2 Q5S007 leucine rich repeat kinase 2 Kinase 2.6E-30 0.510 0.808
CYP2D6 P10635 cytochrome P450 family 2 subfamily D member 6 1.1E-25 0.437 0.885
BCHE P06276 butyrylcholinesterase 1.1E-13 0.447 0.923
GEMIN4 P57678 gem nuclear organelle associated protein 4 5.9E-13 0.565 0.808
LAMC2 Q13753 laminin subunit gamma 2 Enzyme modulator 2.9E-12 0.389 0.923
TREM2 Q9NZC2 triggering receptor expressed on myeloid cells 2 3.3E-09 0.519 0.769
APEX1 P27695 apurinic/apyrimidinic endodeoxyribonuclease 1 1.9E-07 0.458 0.846
POLD1 P28340 DNA polymerase delta 1, catalytic subunit 2.4E-06 0.507 0.769
CHI3L1 P36222 chitinase 3 like 1 1.1E-05 0.419 0.885
CLU P10909 clusterin 7.8E-05 0.426 0.885
SMUG1 Q53HV7 single-strand-selective monofunctional uracil-DNA glycosylase 1 4.5E-04 0.322 0.923
PSEN2 P49810 presenilin 2 Enzyme 5.4E-04 0.550 0.654
APOD P05090 apolipoprotein D 5.4E-04 0.584 0.577
TFPI2 P48307 tissue factor pathway inhibitor 2 Enzyme modulator 8.4E-04 0.521 0.769
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962
SUCLA2 Q9P2R7 succinate-CoA ligase ADP-forming subunit beta Enzyme 2.3E-03 0.566 0.654
CFDP1 Q9UEE9 craniofacial development protein 1 3.7E-03 0.619 0.615
MAPT P10636 microtubule associated protein tau 6.0E-03 0.446 0.923
MCIDAS D6RGH6 multiciliate differentiation and DNA synthesis associated cell cycle protein 1.3E-02 0.566 0.769
HCRT O43612 hypocretin neuropeptide precursor 2.9E-02 0.500 0.808
APP P05067 amyloid beta precursor protein Enzyme modulator 4.7E-02 0.422 0.846