Disease: Familial Alzheimer Disease (FAD)
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ACE P12821 angiotensin I converting enzyme Enzyme 1.0E-37 0.328 0.923
ACHE P22303 acetylcholinesterase (Cartwright blood group) Enzyme 1.00 0.445 0.885
APOC1 P02654 apolipoprotein C1 0.22 0.581 0.577
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962
APP P05067 amyloid beta precursor protein Enzyme modulator 4.7E-02 0.422 0.846
ATP5F1A P25705 ATP synthase F1 subunit alpha Transporter 1.00 0.604 0.731
BCHE P06276 butyrylcholinesterase 1.1E-13 0.447 0.923
BRCA1 P38398 BRCA1 DNA repair associated Enzyme 9.2E-29 0.367 0.923
C9orf72 Q96LT7 C9orf72-SMCR8 complex subunit 1.1E-06 0.496 0.769
CASP3 P42574 caspase 3 Enzyme 0.10 0.351 0.923
CDK5R1 Q15078 cyclin dependent kinase 5 regulatory subunit 1 Enzyme modulator 0.91 0.529 0.808
CLU P10909 clusterin 7.8E-05 0.426 0.885
CSF2 P04141 colony stimulating factor 2 Signaling 0.83 0.330 0.962
CTSD P07339 cathepsin D Enzyme 9.2E-04 0.478 0.846
CYP2D6 P10635 cytochrome P450 family 2 subfamily D member 6 1.1E-25 0.437 0.885
EIF2AK3 Q9NZJ5 eukaryotic translation initiation factor 2 alpha kinase 3 Kinase 2.8E-03 0.501 0.808
ERBB4 Q15303 erb-b2 receptor tyrosine kinase 4 Kinase 1.00 0.455 0.846
GFAP P14136 glial fibrillary acidic protein 1.5E-06 0.421 0.885
GSK3B P49841 glycogen synthase kinase 3 beta Kinase 0.96 0.430 0.846
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885
ITM2B Q9Y287 integral membrane protein 2B 0.63 0.617 0.654
LAMC2 Q13753 laminin subunit gamma 2 Enzyme modulator 2.9E-12 0.389 0.923
LEP P41159 leptin 0.46 0.349 0.846
MAPK3 P27361 mitogen-activated protein kinase 3 Kinase 3.7E-02 0.379 0.885
MAPK8 P45983 mitogen-activated protein kinase 8 Kinase 1.00 0.397 0.885