Disease: Hereditary Breast and Ovarian Cancer Syndrome
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
BRCA3 breast cancer 3 0.705 0.269
ABRAXAS1 Q6UWZ7 abraxas 1, BRCA1 A complex subunit 5.1E-07 0.760 0.269
RAD51D O75771 RAD51 paralog D 1.1E-09 0.674 0.385
KRT88P keratin 88 pseudogene 0.705 0.385
EMSY Q7Z589 EMSY transcriptional repressor, BRCA2 interacting 1.00 0.628 0.423
BARD1 Q99728 BRCA1 associated RING domain 1 1.4E-24 0.597 0.538
HSD17B1 P14061 hydroxysteroid 17-beta dehydrogenase 1 Enzyme 1.3E-04 0.610 0.615
RAD51C O43502 RAD51 paralog C 6.2E-14 0.533 0.692
FANCA O15360 FA complementation group A 1.6E-68 0.505 0.731
MSH6 P52701 mutS homolog 6 Nucleic acid binding 3.7E-05 0.462 0.731
BRIP1 Q9BX63 BRCA1 interacting protein C-terminal helicase 1 Enzyme 6.2E-17 0.507 0.731
MSH3 P20585 mutS homolog 3 Nucleic acid binding 7.4E-31 0.474 0.769
RAD51B O15315 RAD51 paralog B 2.1E-15 0.556 0.769
PALB2 Q86YC2 partner and localizer of BRCA2 3.0E-19 0.485 0.769
CDH1 P12830 cadherin 1 0.15 0.401 0.808
MLH1 P40692 mutL homolog 1 Nucleic acid binding 3.4E-05 0.399 0.808
MRE11 P49959 MRE11 homolog, double strand break repair nuclease 1.3E-12 0.527 0.808
MSH2 P43246 mutS homolog 2 Nucleic acid binding 0.90 0.406 0.808
NBN O60934 nibrin Nucleic acid binding 2.2E-16 0.467 0.808
PMS2 P54278 PMS1 homolog 2, mismatch repair system component Nucleic acid binding 4.5E-27 0.484 0.808
RAD50 Q92878 RAD50 double strand break repair protein 3.4E-27 0.556 0.808
CHEK2 O96017 checkpoint kinase 2 Kinase 1.2E-24 0.460 0.808
AR P10275 androgen receptor Nuclear receptor 0.99 0.351 0.846
BRCA2 P51587 BRCA2 DNA repair associated Nucleic acid binding 2.4E-25 0.379 0.846
COL11A2 P13942 collagen type XI alpha 2 chain 0.70 0.435 0.846