Source: ALL
Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
BRCA3 | breast cancer 3 | 0.705 | 0.269 | |||
KRT88P | keratin 88 pseudogene | 0.705 | 0.385 | |||
RAD51B | O15315 | RAD51 paralog B | 2.1E-15 | 0.556 | 0.769 | |
FANCA | O15360 | FA complementation group A | 1.6E-68 | 0.505 | 0.731 | |
RAD51C | O43502 | RAD51 paralog C | 6.2E-14 | 0.533 | 0.692 | |
NBN | O60934 | nibrin | Nucleic acid binding | 2.2E-16 | 0.467 | 0.808 |
RAD51D | O75771 | RAD51 paralog D | 1.1E-09 | 0.674 | 0.385 | |
CHEK2 | O96017 | checkpoint kinase 2 | Kinase | 1.2E-24 | 0.460 | 0.808 |
HRAS | P01112 | HRas proto-oncogene, GTPase | Enzyme modulator | 8.0E-02 | 0.378 | 0.885 |
KRAS | P01116 | KRAS proto-oncogene, GTPase | Enzyme modulator | 7.9E-04 | 0.320 | 0.923 |
ERBB2 | P04626 | erb-b2 receptor tyrosine kinase 2 | Kinase | 6.0E-03 | 0.328 | 0.923 |
TP53 | P04637 | tumor protein p53 | Transcription factor | 0.53 | 0.236 | 0.962 |
PARP1 | P09874 | poly(ADP-ribose) polymerase 1 | 3.3E-04 | 0.389 | 0.923 | |
AR | P10275 | androgen receptor | Nuclear receptor | 0.99 | 0.351 | 0.846 |
CDH1 | P12830 | cadherin 1 | 0.15 | 0.401 | 0.808 | |
COL11A2 | P13942 | collagen type XI alpha 2 chain | 0.70 | 0.435 | 0.846 | |
HSD17B1 | P14061 | hydroxysteroid 17-beta dehydrogenase 1 | Enzyme | 1.3E-04 | 0.610 | 0.615 |
MSH3 | P20585 | mutS homolog 3 | Nucleic acid binding | 7.4E-31 | 0.474 | 0.769 |
APC | P25054 | APC regulator of WNT signaling pathway | 1.00 | 0.373 | 0.962 | |
BRCA1 | P38398 | BRCA1 DNA repair associated | Enzyme | 9.2E-29 | 0.367 | 0.923 |
MLH1 | P40692 | mutL homolog 1 | Nucleic acid binding | 3.4E-05 | 0.399 | 0.808 |
CDKN2A | P42771 Q8N726 | cyclin dependent kinase inhibitor 2A | 0.39 | 0.300 | 0.885 | |
MSH2 | P43246 | mutS homolog 2 | Nucleic acid binding | 0.90 | 0.406 | 0.808 |
MRE11 | P49959 | MRE11 homolog, double strand break repair nuclease | 1.3E-12 | 0.527 | 0.808 | |
BRCA2 | P51587 | BRCA2 DNA repair associated | Nucleic acid binding | 2.4E-25 | 0.379 | 0.846 |