Disease: Clinodactyly of the 5th finger
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923
FGFR2 P21802 fibroblast growth factor receptor 2 Kinase 1.00 0.380 0.808
FGFR3 P22607 fibroblast growth factor receptor 3 Kinase 1.6E-05 0.391 0.846
TWIST1 Q15672 twist family bHLH transcription factor 1 Transcription factor 0.34 0.397 0.846
CREBBP Q92793 CREB binding protein 1.00 0.428 0.808
BMP2 P12643 bone morphogenetic protein 2 Signaling 0.99 0.432 0.846
WNT5A P41221 Wnt family member 5A Signaling 0.99 0.443 0.808
FLNB O75369 filamin B 6.1E-10 0.458 0.923
GATA4 P43694 GATA binding protein 4 0.49 0.458 0.846
EP300 Q09472 E1A binding protein p300 1.00 0.459 0.846
EHMT1 Q9H9B1 euchromatic histone lysine methyltransferase 1 Epigenetic regulator 1.00 0.460 0.808
GPC3 P51654 glypican 3 1.00 0.466 0.808
LIG4 P49917 DNA ligase 4 4.2E-06 0.478 0.846
ROR2 Q01974 receptor tyrosine kinase like orphan receptor 2 Kinase 1.2E-04 0.498 0.731
SATB2 Q9UPW6 SATB homeobox 2 Transcription factor 1.00 0.503 0.769
GDF5 P43026 growth differentiation factor 5 Signaling 0.67 0.511 0.692
NOG Q13253 noggin 0.89 0.518 0.731
DVL1 O14640 dishevelled segment polarity protein 1 Signaling 3.7E-06 0.531 0.769
DVL3 Q92997 dishevelled segment polarity protein 3 Signaling 0.39 0.537 0.731
TRPS1 Q9UHF7 transcriptional repressor GATA binding 1 1.00 0.537 0.769
SALL1 Q9NSC2 spalt like transcription factor 1 Transcription factor 1.00 0.539 0.808
RAB23 Q9ULC3 RAB23, member RAS oncogene family 5.6E-03 0.541 0.654
GPC4 O75487 glypican 4 0.93 0.547 0.769
DACT1 Q9NYF0 dishevelled binding antagonist of beta catenin 1 0.40 0.547 0.692
NSUN2 Q08J23 NOP2/Sun RNA methyltransferase 2 Enzyme 2.6E-04 0.559 0.846