Disease: Clinodactyly of the 5th finger
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
DVL1 O14640 dishevelled segment polarity protein 1 Signaling 3.7E-06 0.531 0.769
FLNB O75369 filamin B 6.1E-10 0.458 0.923
GPC4 O75487 glypican 4 0.93 0.547 0.769
BMP2 P12643 bone morphogenetic protein 2 Signaling 0.99 0.432 0.846
FGFR2 P21802 fibroblast growth factor receptor 2 Kinase 1.00 0.380 0.808
FGFR3 P22607 fibroblast growth factor receptor 3 Kinase 1.6E-05 0.391 0.846
GJA5 P36382 gap junction protein alpha 5 Cell-cell junction 1.8E-02 0.575 0.577
WNT5A P41221 Wnt family member 5A Signaling 0.99 0.443 0.808
GDF5 P43026 growth differentiation factor 5 Signaling 0.67 0.511 0.692
GATA4 P43694 GATA binding protein 4 0.49 0.458 0.846
LIG4 P49917 DNA ligase 4 4.2E-06 0.478 0.846
GPC3 P51654 glypican 3 1.00 0.466 0.808
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923
ROR2 Q01974 receptor tyrosine kinase like orphan receptor 2 Kinase 1.2E-04 0.498 0.731
NSUN2 Q08J23 NOP2/Sun RNA methyltransferase 2 Enzyme 2.6E-04 0.559 0.846
EP300 Q09472 E1A binding protein p300 1.00 0.459 0.846
BPTF Q12830 bromodomain PHD finger transcription factor 1.00 0.560 0.769
NOG Q13253 noggin 0.89 0.518 0.731
TWIST1 Q15672 twist family bHLH transcription factor 1 Transcription factor 0.34 0.397 0.846
NXN Q6DKJ4 nucleoredoxin 1.00 0.584 0.577
PACS1 Q6VY07 phosphofurin acidic cluster sorting protein 1 1.00 0.603 0.615
SRCAP Q6ZRS2 Snf2 related CREBBP activator protein 1.00 0.610 0.731
XYLT1 Q86Y38 xylosyltransferase 1 0.92 0.581 0.731
CREBBP Q92793 CREB binding protein 1.00 0.428 0.808
DVL3 Q92997 dishevelled segment polarity protein 3 Signaling 0.39 0.537 0.731