Disease: Hypercholesterolemia
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
CYP4F2 P78329 cytochrome P450 family 4 subfamily F member 2 Enzyme 7.6E-17 0.674 0.308
NPC1L1 Q9UHC9 NPC1 like intracellular cholesterol transporter 1 Transporter 2.3E-20 0.656 0.423
ZPR1 O75312 ZPR1 zinc finger 8.9E-09 0.674 0.462
ABCG8 Q9H221 ATP binding cassette subfamily G member 8 Transporter 2.4E-20 0.573 0.538
ANGPTL3 Q9Y5C1 angiopoietin like 3 Signaling 1.6E-13 0.584 0.577
ABCG5 Q9H222 ATP binding cassette subfamily G member 5 Transporter 3.1E-21 0.592 0.577
SORT1 Q99523 sortilin 1 Transporter 1.00 0.573 0.615
LCAT P04180 lecithin-cholesterol acyltransferase Enzyme 8.1E-02 0.588 0.654
LIPC P11150 lipase C, hepatic type Enzyme 3.3E-07 0.585 0.654
ABCB11 O95342 ATP binding cassette subfamily B member 11 Transporter 1.6E-12 0.566 0.654
HMGCR P04035 3-hydroxy-3-methylglutaryl-CoA reductase 1.00 0.529 0.692
VLDLR P98155 very low density lipoprotein receptor 2.0E-11 0.558 0.692
SH2B3 Q9UQQ2 SH2B adaptor protein 3 1.0E-04 0.527 0.692
CETP P11597 cholesteryl ester transfer protein 1.2E-23 0.512 0.731
LPA P08519 lipoprotein(a) Enzyme 6.6E-89 0.444 0.769
ABCC3 O15438 ATP binding cassette subfamily C member 3 Transporter 1.2E-26 0.517 0.769
PLA2G15 Q8NCC3 phospholipase A2 group XV Enzyme 0.38 0.520 0.769
UGT1A1 P22309 UDP glucuronosyltransferase family 1 member A1 3.3E-06 0.464 0.769
APOB P04114 apolipoprotein B 1.9E-16 0.453 0.808
LEPR P48357 leptin receptor Signaling 0.99 0.433 0.808
ALMS1 Q8TCU4 ALMS1 centrosome and basal body associated protein 4.5E-60 0.559 0.808
PCSK9 Q8NBP7 proprotein convertase subtilisin/kexin type 9 Enzyme 2.7E-17 0.482 0.808
AGTR1 P30556 angiotensin II receptor type 1 G-protein coupled receptor 5.3E-04 0.423 0.846
APP P05067 amyloid beta precursor protein Enzyme modulator 4.7E-02 0.422 0.846
AR P10275 androgen receptor Nuclear receptor 0.99 0.351 0.846