Disease: Hypercholesterolemia
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
APOB P04114 apolipoprotein B 1.9E-16 0.453 0.808
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962
CD40 P25942 CD40 molecule 0.85 0.396 0.846
CETP P11597 cholesteryl ester transfer protein 1.2E-23 0.512 0.731
CYP2B6 P20813 cytochrome P450 family 2 subfamily B member 6 1.9E-10 0.428 0.846
HMGCR P04035 3-hydroxy-3-methylglutaryl-CoA reductase 1.00 0.529 0.692
ICAM1 P05362 intercellular adhesion molecule 1 3.5E-02 0.364 0.962
LDLR P01130 low density lipoprotein receptor 9.8E-24 0.449 0.885
LRP2 P98164 LDL receptor related protein 2 1.00 0.491 0.846
VLDLR P98155 very low density lipoprotein receptor 2.0E-11 0.558 0.692
ALMS1 Q8TCU4 ALMS1 centrosome and basal body associated protein 4.5E-60 0.559 0.808
ZPR1 O75312 ZPR1 zinc finger 8.9E-09 0.674 0.462
SH2B3 Q9UQQ2 SH2B adaptor protein 3 1.0E-04 0.527 0.692
UGT1A1 P22309 UDP glucuronosyltransferase family 1 member A1 3.3E-06 0.464 0.769
ABO P16442 ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase Enzyme 0.427 0.885
ARG1 P05089 arginase 1 Enzyme 3.6E-04 0.476 0.846
CASP3 P42574 caspase 3 Enzyme 0.10 0.351 0.923
ACE P12821 angiotensin I converting enzyme Enzyme 1.0E-37 0.328 0.923
DHCR7 Q9UBM7 7-dehydrocholesterol reductase Enzyme 3.9E-13 0.500 0.846
GSR P00390 glutathione-disulfide reductase Enzyme 1.3E-06 0.494 0.846
LCAT P04180 lecithin-cholesterol acyltransferase Enzyme 8.1E-02 0.588 0.654
LIPC P11150 lipase C, hepatic type Enzyme 3.3E-07 0.585 0.654
LPA P08519 lipoprotein(a) Enzyme 6.6E-89 0.444 0.769
CYP4F2 P78329 cytochrome P450 family 4 subfamily F member 2 Enzyme 7.6E-17 0.674 0.308
PLA2G15 Q8NCC3 phospholipase A2 group XV Enzyme 0.38 0.520 0.769