Disease: Metastatic non-small cell lung cancer
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
MIR375 microRNA 375 0.476 0.769
ATM Q13315 ATM serine/threonine kinase Kinase 5.6E-47 0.374 0.885
CYP2C19 P33261 cytochrome P450 family 2 subfamily C member 19 6.5E-20 0.467 0.846
MMP9 P14780 matrix metallopeptidase 9 Enzyme 1.9E-17 0.305 0.923
EGF P01133 epidermal growth factor 8.5E-17 0.357 0.923
MTHFR P42898 methylenetetrahydrofolate reductase 3.2E-10 0.337 0.885
CEACAM5 P06731 CEA cell adhesion molecule 5 4.2E-10 0.420 0.846
SELE P16581 selectin E 7.9E-10 0.447 0.808
EPCAM P16422 epithelial cell adhesion molecule 1.3E-07 0.451 0.885
ERCC1 P07992 ERCC excision repair 1, endonuclease non-catalytic subunit Enzyme 1.6E-07 0.445 0.846
PRL P01236 prolactin Signaling 2.9E-07 0.406 0.885
NTRK1 P04629 neurotrophic receptor tyrosine kinase 1 Kinase 2.0E-06 0.422 0.808
SPP1 P10451 secreted phosphoprotein 1 2.1E-06 0.353 0.885
ALK Q9UM73 ALK receptor tyrosine kinase Kinase 3.2E-06 0.396 0.846
VEGFA P15692 vascular endothelial growth factor A Signaling 2.4E-05 0.266 0.923
ITGAV P06756 integrin subunit alpha V 2.3E-04 0.526 0.769
PARP1 P09874 poly(ADP-ribose) polymerase 1 3.3E-04 0.389 0.923
SMUG1 Q53HV7 single-strand-selective monofunctional uracil-DNA glycosylase 1 4.5E-04 0.322 0.923
FOXM1 Q08050 forkhead box M1 7.4E-04 0.441 0.769
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923
SLC5A5 Q92911 solute carrier family 5 member 5 Transporter 2.9E-03 0.499 0.769
CRP P02741 C-reactive protein 3.7E-03 0.299 0.962
ERBB2 P04626 erb-b2 receptor tyrosine kinase 2 Kinase 6.0E-03 0.328 0.923
CXCR4 P61073 C-X-C motif chemokine receptor 4 G-protein coupled receptor 1.8E-02 0.362 0.923
CD274 Q9NZQ7 CD274 molecule Receptor 1.9E-02 0.324 0.923