Disease: Metastatic non-small cell lung cancer
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
MIR375 microRNA 375 0.476 0.769
TNFSF14 O43557 TNF superfamily member 14 Signaling 5.2E-02 0.529 0.769
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923
EGF P01133 epidermal growth factor 8.5E-17 0.357 0.923
PRL P01236 prolactin Signaling 2.9E-07 0.406 0.885
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
CRP P02741 C-reactive protein 3.7E-03 0.299 0.962
ESR1 P03372 estrogen receptor 1 Nuclear receptor 1.00 0.324 0.962
S100B P04271 S100 calcium binding protein B Calcium-binding protein 4.4E-02 0.383 0.923
ERBB2 P04626 erb-b2 receptor tyrosine kinase 2 Kinase 6.0E-03 0.328 0.923
NTRK1 P04629 neurotrophic receptor tyrosine kinase 1 Kinase 2.0E-06 0.422 0.808
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
TYMS P04818 thymidylate synthetase Enzyme 0.72 0.425 0.846
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885
CEACAM5 P06731 CEA cell adhesion molecule 5 4.2E-10 0.420 0.846
ITGAV P06756 integrin subunit alpha V 2.3E-04 0.526 0.769
RET P07949 ret proto-oncogene Kinase 1.00 0.392 0.885
ERCC1 P07992 ERCC excision repair 1, endonuclease non-catalytic subunit Enzyme 1.6E-07 0.445 0.846
THBS1 P07996 thrombospondin 1 1.00 0.407 0.885
MET P08581 MET proto-oncogene, receptor tyrosine kinase Kinase 0.97 0.380 0.846
PDGFRB P09619 platelet derived growth factor receptor beta Kinase 0.90 0.416 0.846
PARP1 P09874 poly(ADP-ribose) polymerase 1 3.3E-04 0.389 0.923
SPP1 P10451 secreted phosphoprotein 1 2.1E-06 0.353 0.885
CDH1 P12830 cadherin 1 0.15 0.401 0.808