Disease: Muscle Spasticity
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
EXOSC8 Q96B26 exosome component 8 Enzyme 6.9E-15 0.736 0.269
TAF2 Q6P1X5 TATA-box binding protein associated factor 2 Enzyme 2.6E-03 0.743 0.308
DNAJC6 O75061 DnaJ heat shock protein family (Hsp40) member C6 1.00 0.641 0.385
CLP1 Q92989 cleavage factor polyribonucleotide kinase subunit 1 Nucleic acid binding 0.20 0.700 0.385
ABHD12 Q8N2K0 abhydrolase domain containing 12 Enzyme 1.9E-05 0.666 0.385
OPA3 Q9H6K4 outer mitochondrial membrane lipid metabolism regulator OPA3 0.57 0.653 0.385
ATXN8OS P0DMR3 ATXN8 opposite strand lncRNA 0.650 0.423
VAPB O95292 VAMP associated protein B and C Transporter 0.58 0.666 0.423
WDR45 Q9Y484 WD repeat domain 45 0.99 0.647 0.423
UNC13A Q9UPW8 unc-13 homolog A 1.00 0.705 0.423
PARS2 Q7L3T8 prolyl-tRNA synthetase 2, mitochondrial Enzyme 4.1E-03 0.644 0.423
ALS2 Q96Q42 alsin Rho guanine nucleotide exchange factor ALS2 8.7E-12 0.647 0.423
SPG16 spastic paraplegia 16 (complicated, X-linked recessive) 0.722 0.423
REEP1 Q9H902 receptor accessory protein 1 Transporter 0.99 0.653 0.423
KCNB1 Q14721 potassium voltage-gated channel subfamily B member 1 Ion channel 1.00 0.650 0.462
KCNC3 Q14003 potassium voltage-gated channel subfamily C member 3 Ion channel 0.21 0.705 0.462
AFG3L2 Q9Y4W6 AFG3 like matrix AAA peptidase subunit 2 Enzyme 5.3E-09 0.588 0.462
UBQLN2 Q9UHD9 ubiquilin 2 0.85 0.656 0.462
NIPA1 Q7RTP0 NIPA magnesium transporter 1 Transporter 5.9E-03 0.682 0.462
CHCHD10 Q8WYQ3 coiled-coil-helix-coiled-coil-helix domain containing 10 5.4E-06 0.623 0.462
DARS1 P14868 aspartyl-tRNA synthetase 1 Enzyme 8.5E-06 0.711 0.500
DCTN1 Q14203 dynactin subunit 1 Chaperone 8.4E-02 0.597 0.500
GAN Q9H2C0 gigaxonin 2.5E-02 0.674 0.500
TAF15 Q92804 TATA-box binding protein associated factor 15 Nucleic acid binding 0.17 0.626 0.500
PPT2 Q9UMR5 palmitoyl-protein thioesterase 2 Enzyme 4.5E-03 0.751 0.500