Disease: Muscle Spasticity
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
MS multiple sclerosis 0.599 0.692
SPG16 spastic paraplegia 16 (complicated, X-linked recessive) 0.722 0.423
PRNP F7VJQ1 P04156 prion protein 6.3E-04 0.445 0.923
CACNA1A O00555 calcium voltage-gated channel subunit alpha1 A Ion channel 1.00 0.489 0.769
DDX3X O00571 DEAD-box helicase 3 X-linked 1.00 0.537 0.769
CIT O14578 citron rho-interacting serine/threonine kinase Kinase 1.00 0.555 0.692
POLR3A O14802 RNA polymerase III subunit A Enzyme 1.3E-23 0.538 0.769
SPTBN2 O15020 spectrin beta, non-erythrocytic 2 9.9E-05 0.619 0.731
NPC1 O15118 NPC intracellular cholesterol transporter 1 Transporter 6.5E-06 0.518 0.692
ATXN7 O15265 ataxin 7 0.96 0.581 0.654
GRIN2D O15399 glutamate ionotropic receptor NMDA type subunit 2D Ion channel 1.00 0.650 0.538
SYNJ1 O43426 synaptojanin 1 Enzyme 0.43 0.576 0.577
HTRA2 O43464 HtrA serine peptidase 2 3.6E-03 0.542 0.692
CACNA1G O43497 calcium voltage-gated channel subunit alpha1 G Ion channel 1.00 0.590 0.577
TYROBP O43914 transmembrane immune signaling adaptor TYROBP 0.20 0.573 0.769
TIMM8A O60220 translocase of inner mitochondrial membrane 8A 0.65 0.510 0.846
PRKN O60260 parkin RBR E3 ubiquitin protein ligase Enzyme 6.9E-07 0.431 0.846
PLA2G6 O60733 phospholipase A2 group VI Enzyme modulator 2.5E-10 0.476 0.846
PQBP1 O60828 polyglutamine binding protein 1 Transcription factor 0.79 0.570 0.654
DNAJC6 O75061 DnaJ heat shock protein family (Hsp40) member C6 1.00 0.641 0.385
ATP6AP2 O75787 ATPase H+ transporting accessory protein 2 Receptor 0.87 0.525 0.769
EPM2A O95278 EPM2A glucan phosphatase, laforin 8.7E-06 0.608 0.577
VAPB O95292 VAMP associated protein B and C Transporter 0.58 0.666 0.423
SOD1 P00441 superoxide dismutase 1 Enzyme 0.18 0.379 0.962
PNP P00491 purine nucleoside phosphorylase Enzyme 7.0E-06 0.527 0.885