Disease: Major Depressive Disorder
Source: CURATED ×
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
VEGFA P15692 vascular endothelial growth factor A Signaling 2.4E-05 0.266 0.923
PTGS2 P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1.00 0.314 0.962
HIF1A Q16665 hypoxia inducible factor 1 subunit alpha Transcription factor 0.98 0.327 0.923
MTHFR P42898 methylenetetrahydrofolate reductase 3.2E-10 0.337 0.885
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923
S100B P04271 S100 calcium binding protein B Calcium-binding protein 4.4E-02 0.383 0.923
NR3C1 P04150 nuclear receptor subfamily 3 group C member 1 Nuclear receptor 0.97 0.393 0.885
SST P61278 somatostatin Signaling 0.34 0.399 0.885
COMT P21964 catechol-O-methyltransferase Enzyme 1.1E-06 0.400 0.923
HSP90AA1 P07900 heat shock protein 90 alpha family class A member 1 Chaperone 0.86 0.411 0.923
HP P00738 haptoglobin Enzyme 1.7E-05 0.412 0.885
NCAM1 P13591 neural cell adhesion molecule 1 1.00 0.415 0.885
TAC1 P20366 tachykinin precursor 1 0.75 0.424 0.923
SLC6A4 P31645 solute carrier family 6 member 4 Transporter 0.25 0.429 0.808
GSK3B P49841 glycogen synthase kinase 3 beta Kinase 0.96 0.430 0.846
DRD2 P14416 dopamine receptor D2 G-protein coupled receptor 0.75 0.436 0.846
CYP2D6 P10635 cytochrome P450 family 2 subfamily D member 6 1.1E-25 0.437 0.885
CRH P06850 corticotropin releasing hormone Signaling 0.72 0.439 0.808
NPY P01303 neuropeptide Y Signaling 0.14 0.447 0.846
TH P07101 tyrosine hydroxylase 1.7E-06 0.462 0.885
CREB1 P16220 cAMP responsive element binding protein 1 1.00 0.463 0.885
CLOCK O15516 clock circadian regulator 1.00 0.463 0.885
MAOA P21397 monoamine oxidase A 1.00 0.465 0.769
HTR2A P28223 5-hydroxytryptamine receptor 2A G-protein coupled receptor 0.51 0.473 0.846