Disease: Major Depressive Disorder
Source: CURATED ×
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
TSNAX-DISC1 TSNAX-DISC1 readthrough (NMD candidate) 0.729 0.154
CYP2D6 P10635 cytochrome P450 family 2 subfamily D member 6 1.1E-25 0.437 0.885
GNB3 P16520 G protein subunit beta 3 Enzyme 3.3E-11 0.518 0.808
HTR3A P46098 5-hydroxytryptamine receptor 3A Ion channel 1.7E-10 0.608 0.538
MTHFR P42898 methylenetetrahydrofolate reductase 3.2E-10 0.337 0.885
DBH P09172 dopamine beta-hydroxylase 3.3E-10 0.511 0.846
DRD4 P21917 dopamine receptor D4 G-protein coupled receptor 9.3E-09 0.517 0.577
TPH2 Q8IWU9 tryptophan hydroxylase 2 2.5E-07 0.546 0.654
TPH1 P17752 tryptophan hydroxylase 1 3.2E-07 0.553 0.731
ADCY7 P51828 adenylate cyclase 7 9.5E-07 0.656 0.462
COMT P21964 catechol-O-methyltransferase Enzyme 1.1E-06 0.400 0.923
DISC1 Q9NRI5 DISC1 scaffold protein 1.7E-06 0.548 0.769
TH P07101 tyrosine hydroxylase 1.7E-06 0.462 0.885
GAL P22466 galanin and GMAP prepropeptide 4.4E-06 0.493 0.846
DTNBP1 Q96EV8 dystrobrevin binding protein 1 6.8E-06 0.588 0.615
HP P00738 haptoglobin Enzyme 1.7E-05 0.412 0.885
VEGFA P15692 vascular endothelial growth factor A Signaling 2.4E-05 0.266 0.923
CRHR1 P34998 corticotropin releasing hormone receptor 1 3.8E-05 0.517 0.769
DAOA P59103 D-amino acid oxidase activator 1.4E-04 0.678 0.346
PDYN P01213 prodynorphin Signaling 1.7E-04 0.535 0.577
DRD3 P35462 dopamine receptor D3 G-protein coupled receptor 2.4E-03 0.529 0.692
PROK2 Q9HC23 prokineticin 2 Signaling 1.4E-02 0.555 0.769
SLC5A7 Q9GZV3 solute carrier family 5 member 7 Transporter 1.5E-02 0.597 0.654
HTR2C P28335 5-hydroxytryptamine receptor 2C G-protein coupled receptor 3.7E-02 0.555 0.692
S100B P04271 S100 calcium binding protein B Calcium-binding protein 4.4E-02 0.383 0.923