Disease: Absence of secondary sex characteristics
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ANOS1 P23352 anosmin 1 1.00 0.537 0.769
CHD7 Q9P2D1 chromodomain helicase DNA binding protein 7 1.00 0.441 0.846
CYB5A P00167 cytochrome b5 type A Enzyme 1.6E-03 0.601 0.654
CYP11A1 P05108 cytochrome P450 family 11 subfamily A member 1 5.5E-07 0.547 0.731
CYP17A1 P05093 cytochrome P450 family 17 subfamily A member 1 2.6E-04 0.462 0.769
DMRT3 Q9NQL9 doublesex and mab-3 related transcription factor 3 6.2E-06 0.653 0.500
DUSP6 Q16828 dual specificity phosphatase 6 0.98 0.511 0.846
ESR1 P03372 estrogen receptor 1 Nuclear receptor 1.00 0.324 0.962
FGF17 O60258 fibroblast growth factor 17 Signaling 0.96 0.593 0.692
FGF8 P55075 fibroblast growth factor 8 Signaling 0.68 0.507 0.769
FGFR1 P11362 fibroblast growth factor receptor 1 Kinase 1.00 0.362 0.885
GATA4 P43694 GATA binding protein 4 0.49 0.458 0.846
GLI2 P10070 GLI family zinc finger 2 0.97 0.446 0.846
GNRH1 P01148 gonadotropin releasing hormone 1 0.15 0.524 0.731
GNRHR P30968 gonadotropin releasing hormone receptor G-protein coupled receptor 6.8E-02 0.540 0.654
HESX1 Q9UBX0 HESX homeobox 1 8.0E-04 0.561 0.654
HS6ST1 O60243 heparan sulfate 6-O-sulfotransferase 1 Enzyme 0.92 0.617 0.731
HSD3B2 P26439 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 Enzyme 7.2E-08 0.582 0.500
KISS1 Q15726 KiSS-1 metastasis suppressor 0.49 0.507 0.808
KISS1R Q969F8 KISS1 receptor G-protein coupled receptor 0.44 0.515 0.769
LHX4 Q969G2 LIM homeobox 4 Nucleic acid binding 1.8E-02 0.621 0.462
MAP3K1 Q13233 mitogen-activated protein kinase kinase kinase 1 Kinase 1.00 0.538 0.731
NR0B1 P51843 nuclear receptor subfamily 0 group B member 1 Nuclear receptor 0.97 0.494 0.808
NR5A1 Q13285 nuclear receptor subfamily 5 group A member 1 Nuclear receptor 0.99 0.479 0.731
NSMF Q6X4W1 NMDA receptor synaptonuclear signaling and neuronal migration factor 0.26 0.606 0.692