Disease: Developmental regression
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
TRNK tRNA 0.608 0.577
IL12A-AS1 IL12A antisense RNA 1 0.633 0.654
PMS2 P54278 PMS1 homolog 2, mismatch repair system component Nucleic acid binding 4.5E-27 0.484 0.808
ERAP1 Q9NZ08 endoplasmic reticulum aminopeptidase 1 Enzyme 2.1E-26 0.556 0.692
FAN1 Q9Y2M0 FANCD2 and FANCI associated nuclease 1 1.7E-25 0.610 0.577
VPS13A Q96RL7 vacuolar protein sorting 13 homolog A 9.3E-22 0.650 0.577
PMS1 P54277 PMS1 homolog 1, mismatch repair system component Nucleic acid binding 1.3E-17 0.569 0.654
MEFV O15553 MEFV innate immuity regulator, pyrin 1.0E-14 0.440 0.885
ARSA P15289 arylsulfatase A Enzyme 1.1E-11 0.448 0.923
C4A P0C0L4 P0C0L5 complement C4A (Rodgers blood group) Enzyme modulator 1.5E-11 0.563 0.769
EIF2B2 P49770 eukaryotic translation initiation factor 2B subunit beta 2.1E-10 0.647 0.538
FTL P02792 ferritin light chain Storage 1.7E-09 0.559 0.692
POLG P54098 DNA polymerase gamma, catalytic subunit Enzyme 2.1E-09 0.457 0.846
TREM2 Q9NZC2 triggering receptor expressed on myeloid cells 2 3.3E-09 0.519 0.769
TLR4 O00206 toll like receptor 4 4.6E-09 0.321 0.962
MLH3 Q9UHC1 mutL homolog 3 Nucleic acid binding 4.9E-08 0.582 0.538
NDUFAF6 Q330K2 NADH:ubiquinone oxidoreductase complex assembly factor 6 9.1E-08 0.659 0.615
EPCAM P16422 epithelial cell adhesion molecule 1.3E-07 0.451 0.885
GBA P04062 glucosylceramidase beta 1.4E-06 0.500 0.808
PEX6 Q13608 peroxisomal biogenesis factor 6 6.3E-06 0.547 0.731
SEMA4A Q9H3S1 semaphorin 4A Signaling 1.8E-05 0.569 0.692
MLH1 P40692 mutL homolog 1 Nucleic acid binding 3.4E-05 0.399 0.808
MSH6 P52701 mutS homolog 6 Nucleic acid binding 3.7E-05 0.462 0.731
HLA-B P01889 major histocompatibility complex, class I, B 3.9E-05 0.379 0.885
EIF2B1 Q14232 eukaryotic translation initiation factor 2B subunit alpha 7.6E-05 0.663 0.538