Disease: Substance abuse problem
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
MAOA P21397 monoamine oxidase A 1.00 0.465 0.769
HOMER1 Q86YM7 homer scaffold protein 1 1.00 0.636 0.538
GRM5 P41594 glutamate metabotropic receptor 5 G-protein coupled receptor 1.00 0.525 0.846
SLC6A3 Q01959 solute carrier family 6 member 3 Transporter 1.00 0.453 0.885
GABRA2 P47869 gamma-aminobutyric acid type A receptor subunit alpha2 Ion channel 1.00 0.641 0.346
SNCA P37840 synuclein alpha Transporter 0.88 0.427 0.885
DRD2 P14416 dopamine receptor D2 G-protein coupled receptor 0.75 0.436 0.846
NCS1 P62166 neuronal calcium sensor 1 0.66 0.656 0.615
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923
CNR1 P21554 cannabinoid receptor 1 G-protein coupled receptor 0.51 0.446 0.808
SLC6A4 P31645 solute carrier family 6 member 4 Transporter 0.25 0.429 0.808
HTR1B P28222 5-hydroxytryptamine receptor 1B G-protein coupled receptor 0.19 0.551 0.769
SIGMAR1 Q99720 sigma non-opioid intracellular receptor 1 0.17 0.544 0.808
NPY P01303 neuropeptide Y Signaling 0.14 0.447 0.846
GRM2 Q14416 glutamate metabotropic receptor 2 G-protein coupled receptor 0.12 0.582 0.577
SLC18A2 Q05940 solute carrier family 18 member A2 Transporter 7.6E-02 0.554 0.769
HTR2C P28335 5-hydroxytryptamine receptor 2C G-protein coupled receptor 3.7E-02 0.555 0.692
HOMER2 Q9NSB8 homer scaffold protein 2 9.4E-03 0.691 0.500
OPRD1 P41143 opioid receptor delta 1 G-protein coupled receptor 3.3E-03 0.604 0.731
DRD3 P35462 dopamine receptor D3 G-protein coupled receptor 2.4E-03 0.529 0.692
PDYN P01213 prodynorphin Signaling 1.7E-04 0.535 0.577
NPS P0C0P6 neuropeptide S 1.4E-04 0.619 0.615
POMC P01189 proopiomelanocortin 1.2E-04 0.356 0.846
OPRK1 P41145 opioid receptor kappa 1 G-protein coupled receptor 4.1E-05 0.555 0.615
CHRNA5 P30532 cholinergic receptor nicotinic alpha 5 subunit Ion channel 2.1E-06 0.593 0.577