Disease: Substance abuse problem
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
DNAH8 Q96JB1 dynein axonemal heavy chain 8 Enzyme 1.1E-60 0.556 0.731
BCHE P06276 butyrylcholinesterase 1.1E-13 0.447 0.923
OPRM1 P35372 opioid receptor mu 1 G-protein coupled receptor 7.9E-11 0.457 0.808
DBH P09172 dopamine beta-hydroxylase 3.3E-10 0.511 0.846
DRD4 P21917 dopamine receptor D4 G-protein coupled receptor 9.3E-09 0.517 0.577
PRL P01236 prolactin Signaling 2.9E-07 0.406 0.885
COMT P21964 catechol-O-methyltransferase Enzyme 1.1E-06 0.400 0.923
CHRNA5 P30532 cholinergic receptor nicotinic alpha 5 subunit Ion channel 2.1E-06 0.593 0.577
OPRK1 P41145 opioid receptor kappa 1 G-protein coupled receptor 4.1E-05 0.555 0.615
POMC P01189 proopiomelanocortin 1.2E-04 0.356 0.846
NPS P0C0P6 neuropeptide S 1.4E-04 0.619 0.615
PDYN P01213 prodynorphin Signaling 1.7E-04 0.535 0.577
DRD3 P35462 dopamine receptor D3 G-protein coupled receptor 2.4E-03 0.529 0.692
OPRD1 P41143 opioid receptor delta 1 G-protein coupled receptor 3.3E-03 0.604 0.731
HOMER2 Q9NSB8 homer scaffold protein 2 9.4E-03 0.691 0.500
HTR2C P28335 5-hydroxytryptamine receptor 2C G-protein coupled receptor 3.7E-02 0.555 0.692
SLC18A2 Q05940 solute carrier family 18 member A2 Transporter 7.6E-02 0.554 0.769
GRM2 Q14416 glutamate metabotropic receptor 2 G-protein coupled receptor 0.12 0.582 0.577
NPY P01303 neuropeptide Y Signaling 0.14 0.447 0.846
SIGMAR1 Q99720 sigma non-opioid intracellular receptor 1 0.17 0.544 0.808
HTR1B P28222 5-hydroxytryptamine receptor 1B G-protein coupled receptor 0.19 0.551 0.769
SLC6A4 P31645 solute carrier family 6 member 4 Transporter 0.25 0.429 0.808
CNR1 P21554 cannabinoid receptor 1 G-protein coupled receptor 0.51 0.446 0.808
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923
NCS1 P62166 neuronal calcium sensor 1 0.66 0.656 0.615