Disease: Substance abuse problem
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
BCHE P06276 butyrylcholinesterase 1.1E-13 0.447 0.923
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923
CHRNA5 P30532 cholinergic receptor nicotinic alpha 5 subunit Ion channel 2.1E-06 0.593 0.577
CNR1 P21554 cannabinoid receptor 1 G-protein coupled receptor 0.51 0.446 0.808
COMT P21964 catechol-O-methyltransferase Enzyme 1.1E-06 0.400 0.923
DBH P09172 dopamine beta-hydroxylase 3.3E-10 0.511 0.846
DNAH8 Q96JB1 dynein axonemal heavy chain 8 Enzyme 1.1E-60 0.556 0.731
DRD2 P14416 dopamine receptor D2 G-protein coupled receptor 0.75 0.436 0.846
DRD3 P35462 dopamine receptor D3 G-protein coupled receptor 2.4E-03 0.529 0.692
DRD4 P21917 dopamine receptor D4 G-protein coupled receptor 9.3E-09 0.517 0.577
GABRA2 P47869 gamma-aminobutyric acid type A receptor subunit alpha2 Ion channel 1.00 0.641 0.346
GRM2 Q14416 glutamate metabotropic receptor 2 G-protein coupled receptor 0.12 0.582 0.577
GRM5 P41594 glutamate metabotropic receptor 5 G-protein coupled receptor 1.00 0.525 0.846
HOMER1 Q86YM7 homer scaffold protein 1 1.00 0.636 0.538
HOMER2 Q9NSB8 homer scaffold protein 2 9.4E-03 0.691 0.500
HTR1B P28222 5-hydroxytryptamine receptor 1B G-protein coupled receptor 0.19 0.551 0.769
HTR2C P28335 5-hydroxytryptamine receptor 2C G-protein coupled receptor 3.7E-02 0.555 0.692
MAOA P21397 monoamine oxidase A 1.00 0.465 0.769
NCS1 P62166 neuronal calcium sensor 1 0.66 0.656 0.615
NPS P0C0P6 neuropeptide S 1.4E-04 0.619 0.615
NPY P01303 neuropeptide Y Signaling 0.14 0.447 0.846
OPRD1 P41143 opioid receptor delta 1 G-protein coupled receptor 3.3E-03 0.604 0.731
OPRK1 P41145 opioid receptor kappa 1 G-protein coupled receptor 4.1E-05 0.555 0.615
OPRM1 P35372 opioid receptor mu 1 G-protein coupled receptor 7.9E-11 0.457 0.808
PDYN P01213 prodynorphin Signaling 1.7E-04 0.535 0.577