Disease: Juvenile Myelomonocytic Leukemia
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962
IL4 P05112 interleukin 4 4.7E-03 0.332 0.962
AR P10275 androgen receptor Nuclear receptor 0.99 0.351 0.846
CXCR4 P61073 C-X-C motif chemokine receptor 4 G-protein coupled receptor 1.8E-02 0.362 0.923
EPO P01588 erythropoietin 1.1E-02 0.381 0.885
JAK2 O60674 Janus kinase 2 Kinase 0.65 0.385 0.885
ALK Q9UM73 ALK receptor tyrosine kinase Kinase 3.2E-06 0.396 0.846
CALR P27797 calreticulin Calcium-binding protein 0.89 0.413 0.923
PDGFRB P09619 platelet derived growth factor receptor beta Kinase 0.90 0.416 0.846
RUNX1 Q01196 RUNX family transcription factor 1 Transcription factor 0.65 0.425 0.808
BCR P11274 BCR activator of RhoGEF and GTPase Enzyme modulator 0.99 0.431 0.885
ABL1 P00519 ABL proto-oncogene 1, non-receptor tyrosine kinase Kinase 1.00 0.432 0.923
NF1 P21359 neurofibromin 1 Enzyme modulator 0.90 0.440 0.885
STAT5B P51692 signal transducer and activator of transcription 5B Nucleic acid binding 1.00 0.442 0.808
CCR7 P32248 C-C motif chemokine receptor 7 G-protein coupled receptor 5.8E-02 0.443 0.769
STAT5A P42229 signal transducer and activator of transcription 5A Nucleic acid binding 1.00 0.445 0.808
TET2 Q6N021 tet methylcytosine dioxygenase 2 4.3E-54 0.458 0.808
FANCB Q8NB91 FA complementation group B 1.00 0.468 0.769
SF3B1 O75533 splicing factor 3b subunit 1 Nucleic acid binding 1.00 0.511 0.731
MECOM Q03112 MDS1 and EVI1 complex locus 1.00 0.513 0.731
THPO P40225 thrombopoietin 0.20 0.513 0.692
CBL P22681 Cbl proto-oncogene Enzyme 6.1E-04 0.527 0.769
SH2B3 Q9UQQ2 SH2B adaptor protein 3 1.0E-04 0.527 0.692
RARS1 P54136 arginyl-tRNA synthetase 1 3.3E-08 0.604 0.538