Disease: Juvenile Myelomonocytic Leukemia
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
JAK2 O60674 Janus kinase 2 Kinase 0.65 0.385 0.885
SF3B1 O75533 splicing factor 3b subunit 1 Nucleic acid binding 1.00 0.511 0.731
ABL1 P00519 ABL proto-oncogene 1, non-receptor tyrosine kinase Kinase 1.00 0.432 0.923
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962
EPO P01588 erythropoietin 1.1E-02 0.381 0.885
IL4 P05112 interleukin 4 4.7E-03 0.332 0.962
PDGFRB P09619 platelet derived growth factor receptor beta Kinase 0.90 0.416 0.846
AR P10275 androgen receptor Nuclear receptor 0.99 0.351 0.846
BCR P11274 BCR activator of RhoGEF and GTPase Enzyme modulator 0.99 0.431 0.885
NF1 P21359 neurofibromin 1 Enzyme modulator 0.90 0.440 0.885
CBL P22681 Cbl proto-oncogene Enzyme 6.1E-04 0.527 0.769
CALR P27797 calreticulin Calcium-binding protein 0.89 0.413 0.923
CCR7 P32248 C-C motif chemokine receptor 7 G-protein coupled receptor 5.8E-02 0.443 0.769
THPO P40225 thrombopoietin 0.20 0.513 0.692
STAT5A P42229 signal transducer and activator of transcription 5A Nucleic acid binding 1.00 0.445 0.808
STAT5B P51692 signal transducer and activator of transcription 5B Nucleic acid binding 1.00 0.442 0.808
RARS1 P54136 arginyl-tRNA synthetase 1 3.3E-08 0.604 0.538
CXCR4 P61073 C-X-C motif chemokine receptor 4 G-protein coupled receptor 1.8E-02 0.362 0.923
RUNX1 Q01196 RUNX family transcription factor 1 Transcription factor 0.65 0.425 0.808
MECOM Q03112 MDS1 and EVI1 complex locus 1.00 0.513 0.731
TET2 Q6N021 tet methylcytosine dioxygenase 2 4.3E-54 0.458 0.808
FANCB Q8NB91 FA complementation group B 1.00 0.468 0.769
ALK Q9UM73 ALK receptor tyrosine kinase Kinase 3.2E-06 0.396 0.846
SH2B3 Q9UQQ2 SH2B adaptor protein 3 1.0E-04 0.527 0.692