Disease: Ichthyosis, X-Linked
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ANXA5 P08758 annexin A5 3.8E-15 0.458 0.769
TIMM8A O60220 translocase of inner mitochondrial membrane 8A 0.65 0.510 0.846
EGF P01133 epidermal growth factor 8.5E-17 0.357 0.923
HSPB1 P04792 heat shock protein family B (small) member 1 2.8E-07 0.436 0.808
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962
MUC1 P15941 mucin 1, cell surface associated 1.9E-02 0.384 0.885
MLRL Myeloid leukemia-related gene (myeloid tumor suppressor) 0.564 0.769
SMUG1 Q53HV7 single-strand-selective monofunctional uracil-DNA glycosylase 1 4.5E-04 0.322 0.923
BRCA1 P38398 BRCA1 DNA repair associated Enzyme 9.2E-29 0.367 0.923
MMP9 P14780 matrix metallopeptidase 9 Enzyme 1.9E-17 0.305 0.923
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923
HPSE Q9Y251 heparanase Enzyme 2.3E-14 0.425 0.808
TBC1D9 Q6ZT07 TBC1 domain family member 9 Enzyme 2.8E-05 0.399 0.846
HRAS P01112 HRas proto-oncogene, GTPase Enzyme modulator 8.0E-02 0.378 0.885
NRAS P01111 NRAS proto-oncogene, GTPase Enzyme modulator 0.49 0.390 0.808
SERPINE1 P05121 serpin family E member 1 Enzyme modulator 4.4E-02 0.359 0.885
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962
BRAF P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1.00 0.319 0.846
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885
ERBB2 P04626 erb-b2 receptor tyrosine kinase 2 Kinase 6.0E-03 0.328 0.923
FGFR1 P11362 fibroblast growth factor receptor 1 Kinase 1.00 0.362 0.885
KDR P35968 kinase insert domain receptor Kinase 1.00 0.378 0.885
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
PIK3CB P42338 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta Kinase 1.00 0.322 0.885