Disease: Ichthyosis, X-Linked
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
MLRL Myeloid leukemia-related gene (myeloid tumor suppressor) 0.564 0.769
TIMM8A O60220 translocase of inner mitochondrial membrane 8A 0.65 0.510 0.846
CHEK2 O96017 checkpoint kinase 2 Kinase 1.2E-24 0.460 0.808
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885
NRAS P01111 NRAS proto-oncogene, GTPase Enzyme modulator 0.49 0.390 0.808
HRAS P01112 HRas proto-oncogene, GTPase Enzyme modulator 8.0E-02 0.378 0.885
EGF P01133 epidermal growth factor 8.5E-17 0.357 0.923
TGFB1 P01137 transforming growth factor beta 1 Signaling 3.7E-02 0.287 0.962
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962
ALB P02768 albumin Transporter 0.64 0.317 0.962
ERBB2 P04626 erb-b2 receptor tyrosine kinase 2 Kinase 6.0E-03 0.328 0.923
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
HSPB1 P04792 heat shock protein family B (small) member 1 2.8E-07 0.436 0.808
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885
SERPINE1 P05121 serpin family E member 1 Enzyme modulator 4.4E-02 0.359 0.885
ABCB1 P08183 ATP binding cassette subfamily B member 1 Transporter 1.3E-05 0.344 0.885
ANXA5 P08758 annexin A5 3.8E-15 0.458 0.769
LGALS1 P09382 galectin 1 Signaling 4.5E-03 0.435 0.846
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885
FGFR1 P11362 fibroblast growth factor receptor 1 Kinase 1.00 0.362 0.885
MMP9 P14780 matrix metallopeptidase 9 Enzyme 1.9E-17 0.305 0.923
BRAF P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1.00 0.319 0.846
MUC1 P15941 mucin 1, cell surface associated 1.9E-02 0.384 0.885
MAPK1 P28482 mitogen-activated protein kinase 1 Kinase 1.00 0.330 0.923