Disease: Keratoderma, Palmoplantar
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962
BRAF P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1.00 0.319 0.846
NFE2L2 Q16236 nuclear factor, erythroid 2 like 2 Enzyme 3.6E-03 0.357 0.885
TP63 Q9H3D4 tumor protein p63 Transcription factor 1.00 0.362 0.769
CTLA4 P16410 cytotoxic T-lymphocyte associated protein 4 0.94 0.369 0.923
GABPA Q06546 GA binding protein transcription factor subunit alpha Transcription factor 1.00 0.379 0.885
GJA1 P17302 gap junction protein alpha 1 Cell-cell junction 0.16 0.393 0.885
MAP2K7 O14733 mitogen-activated protein kinase kinase 7 Kinase 1.00 0.419 0.808
TNFRSF1B P20333 TNF receptor superfamily member 1B 0.50 0.425 0.885
CD28 P10747 CD28 molecule 0.36 0.436 0.885
GJB2 P29033 gap junction protein beta 2 Cell-cell junction 6.6E-16 0.441 0.846
KEAP1 Q14145 kelch like ECH associated protein 1 3.9E-04 0.475 0.808
TAT P17735 tyrosine aminotransferase 6.9E-03 0.492 0.846
ENPP1 P22413 ectonucleotide pyrophosphatase/phosphodiesterase 1 Enzyme 5.0E-08 0.498 0.808
NLRP1 Q9C000 NLR family pyrin domain containing 1 5.0E-19 0.502 0.769
KRT5 P13647 keratin 5 0.64 0.512 0.731
MBTPS2 O43462 membrane bound transcription factor peptidase, site 2 Enzyme 1.00 0.513 0.769
DSP P15924 desmoplakin Cellular structure 1.00 0.514 0.808
ATP2A2 P16615 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 Transporter 1.00 0.529 0.808
KRT14 P02533 keratin 14 2.0E-04 0.530 0.731
CTSC P53634 cathepsin C Enzyme 1.1E-07 0.541 0.731
CARD14 Q9BXL6 caspase recruitment domain family member 14 1.2E-19 0.546 0.846