BRAF |
P15056
|
B-Raf proto-oncogene, serine/threonine kinase
|
Kinase
|
1.00 |
0.319 |
0.846 |
PTEN |
P60484
|
phosphatase and tensin homolog
|
Enzyme
|
0.26 |
0.305 |
0.923 |
PIK3CA |
P42336
|
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
|
Kinase
|
1.00 |
0.292 |
0.923 |
TP53 |
P04637
|
tumor protein p53
|
Transcription factor
|
0.53 |
0.236 |
0.962 |
CTNNB1 |
P35222
|
catenin beta 1
|
|
1.00 |
0.303 |
0.885 |
BRCA2 |
P51587
|
BRCA2 DNA repair associated
|
Nucleic acid binding
|
2.4E-25 |
0.379 |
0.846 |
KRAS |
P01116
|
KRAS proto-oncogene, GTPase
|
Enzyme modulator
|
7.9E-04 |
0.320 |
0.923 |
PALB2 |
Q86YC2
|
partner and localizer of BRCA2
|
|
3.0E-19 |
0.485 |
0.769 |
CHEK2 |
O96017
|
checkpoint kinase 2
|
Kinase
|
1.2E-24 |
0.460 |
0.808 |
ATM |
Q13315
|
ATM serine/threonine kinase
|
Kinase
|
5.6E-47 |
0.374 |
0.885 |
PMS2 |
P54278
|
PMS1 homolog 2, mismatch repair system component
|
Nucleic acid binding
|
4.5E-27 |
0.484 |
0.808 |
C11orf65 |
Q8NCR3
|
chromosome 11 open reading frame 65
|
|
2.0E-14 |
0.670 |
0.462 |
ERBB2 |
P04626
|
erb-b2 receptor tyrosine kinase 2
|
Kinase
|
6.0E-03 |
0.328 |
0.923 |
BRCA1 |
P38398
|
BRCA1 DNA repair associated
|
Enzyme
|
9.2E-29 |
0.367 |
0.923 |
MRE11 |
P49959
|
MRE11 homolog, double strand break repair nuclease
|
|
1.3E-12 |
0.527 |
0.808 |
MSH2 |
P43246
|
mutS homolog 2
|
Nucleic acid binding
|
0.90 |
0.406 |
0.808 |
MSH6 |
P52701
|
mutS homolog 6
|
Nucleic acid binding
|
3.7E-05 |
0.462 |
0.731 |
FBXO11 |
Q86XK2
|
F-box protein 11
|
Enzyme
|
1.00 |
0.604 |
0.692 |
BRIP1 |
Q9BX63
|
BRCA1 interacting protein C-terminal helicase 1
|
Enzyme
|
6.2E-17 |
0.507 |
0.731 |
NBN |
O60934
|
nibrin
|
Nucleic acid binding
|
2.2E-16 |
0.467 |
0.808 |
TRNT |
|
tRNA
|
|
|
0.729 |
0.538 |
CDH1 |
P12830
|
cadherin 1
|
|
0.15 |
0.401 |
0.808 |
CYTB |
P00156
|
cytochrome b
|
|
|
0.529 |
0.808 |
BARD1 |
Q99728
|
BRCA1 associated RING domain 1
|
|
1.4E-24 |
0.597 |
0.538 |
FANCM |
Q8IYD8
|
FA complementation group M
|
Enzyme
|
2.4E-15 |
0.543 |
0.731 |