Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
MMP9 | P14780 | matrix metallopeptidase 9 | Enzyme | 1.9E-17 | 0.305 | 0.923 |
ACE | P12821 | angiotensin I converting enzyme | Enzyme | 1.0E-37 | 0.328 | 0.923 |
APOE | P02649 | apolipoprotein E | 1.9E-03 | 0.338 | 0.962 | |
MTHFR | P42898 | methylenetetrahydrofolate reductase | 3.2E-10 | 0.337 | 0.885 | |
NOS3 | P29474 | nitric oxide synthase 3 | 6.7E-07 | 0.378 | 0.885 | |
GJA1 | P17302 | gap junction protein alpha 1 | Cell-cell junction | 0.16 | 0.393 | 0.885 |
DNMT1 | P26358 | DNA methyltransferase 1 | Epigenetic regulator | 1.00 | 0.406 | 0.885 |
MMP3 | P08254 | matrix metallopeptidase 3 | Enzyme | 5.7E-15 | 0.408 | 0.885 |
SQSTM1 | Q13501 | sequestosome 1 | 8.6E-04 | 0.428 | 0.885 | |
MAPT | P10636 | microtubule associated protein tau | 6.0E-03 | 0.446 | 0.923 | |
POLG | P54098 | DNA polymerase gamma, catalytic subunit | Enzyme | 2.1E-09 | 0.457 | 0.846 |
CREBBP | Q92793 | CREB binding protein | 1.00 | 0.428 | 0.808 | |
SPG7 | Q9UQ90 | SPG7 matrix AAA peptidase subunit, paraplegin | Enzyme | 2.0E-36 | 0.436 | 0.885 |
GRN | P28799 | granulin precursor | 7.0E-02 | 0.435 | 0.846 | |
MEFV | O15553 | MEFV innate immuity regulator, pyrin | 1.0E-14 | 0.440 | 0.885 | |
ARSA | P15289 | arylsulfatase A | Enzyme | 1.1E-11 | 0.448 | 0.923 |
VCP | P55072 | valosin containing protein | 1.00 | 0.469 | 0.923 | |
PSEN1 | P49768 | presenilin 1 | Enzyme | 0.97 | 0.469 | 0.846 |
CSF1R | P07333 | colony stimulating factor 1 receptor | Kinase | 0.13 | 0.448 | 0.808 |
IFIH1 | Q9BYX4 | interferon induced with helicase C domain 1 | 7.0E-44 | 0.471 | 0.808 | |
KCNQ1 | P51787 | potassium voltage-gated channel subfamily Q member 1 | Ion channel | 4.5E-08 | 0.485 | 0.769 |
C9orf72 | Q96LT7 | C9orf72-SMCR8 complex subunit | 1.1E-06 | 0.496 | 0.769 | |
FKRP | Q9H9S5 | fukutin related protein | 9.8E-06 | 0.513 | 0.731 | |
TYMP | P19971 | thymidine phosphorylase | Enzyme | 1.2E-04 | 0.495 | 0.769 |
YY1 | P25490 | YY1 transcription factor | Transcription factor | 0.99 | 0.481 | 0.808 |