Source: INFERRED ×
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923
PTCH1 Q13635 patched 1 1.00 0.398 0.885
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
BRCA2 P51587 BRCA2 DNA repair associated Nucleic acid binding 2.4E-25 0.379 0.846
SUFU Q9UMX1 SUFU negative regulator of hedgehog signaling 1.00 0.493 0.769
SMAD4 Q13485 SMAD family member 4 Transcription factor 1.00 0.401 0.808
APC P25054 APC regulator of WNT signaling pathway 1.00 0.373 0.962
PALB2 Q86YC2 partner and localizer of BRCA2 3.0E-19 0.485 0.769
BRCA1 P38398 BRCA1 DNA repair associated Enzyme 9.2E-29 0.367 0.923
BRIP1 Q9BX63 BRCA1 interacting protein C-terminal helicase 1 Enzyme 6.2E-17 0.507 0.731
ATM Q13315 ATM serine/threonine kinase Kinase 5.6E-47 0.374 0.885
RAD51C O43502 RAD51 paralog C 6.2E-14 0.533 0.692
HNF1B P35680 HNF1 homeobox B Nucleic acid binding 1.00 0.473 0.808
PMS2 P54278 PMS1 homolog 2, mismatch repair system component Nucleic acid binding 4.5E-27 0.484 0.808
NBN O60934 nibrin Nucleic acid binding 2.2E-16 0.467 0.808
CDKN2A P42771 Q8N726 cyclin dependent kinase inhibitor 2A 0.39 0.300 0.885
CHEK2 O96017 checkpoint kinase 2 Kinase 1.2E-24 0.460 0.808
PTCH2 Q9Y6C5 patched 2 3.4E-16 0.563 0.692
BNC2 Q6ZN30 basonuclin 2 Nucleic acid binding 0.93 0.612 0.615
PALLD Q8WX93 palladin, cytoskeletal associated protein 5.3E-06 0.628 0.615
MUTYH Q9UIF7 mutY DNA glycosylase Enzyme 1.3E-18 0.521 0.769
LINC00824 long intergenic non-protein coding RNA 824 0.695 0.346
USHBP1 Q8N6Y0 USH1 protein network component harmonin binding protein 1 3.0E-17 0.705 0.269
BABAM1 Q9NWV8 BRISC and BRCA1 A complex member 1 0.96 0.678 0.385