Disease: Malignant transformation
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
PVT1 Pvt1 oncogene 0.495 0.731
AURKA O14965 aurora kinase A Kinase 0.87 0.475 0.731
SETD1A O15047 SET domain containing 1A, histone lysine methyltransferase 1.00 0.619 0.615
SMAD7 O15105 SMAD family member 7 Transcription factor 0.55 0.470 0.769
JAK2 O60674 Janus kinase 2 Kinase 0.65 0.385 0.885
CBFA2T3 O75081 CBFA2/RUNX1 partner transcriptional co-repressor 3 Transcription factor 4.8E-02 0.638 0.462
RGS11 O94810 regulator of G protein signaling 11 7.3E-14 0.805 0.154
AP2A1 O95782 adaptor related protein complex 2 subunit alpha 1 Receptor 1.00 0.641 0.500
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962
SLC4A1 P02730 solute carrier family 4 member 1 (Diego blood group) Transporter 0.85 0.522 0.731
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
HMGB1 P09429 high mobility group box 1 Nucleic acid binding 0.82 0.368 0.923
MYB P10242 MYB proto-oncogene, transcription factor 0.82 0.490 0.692
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885
KIT P10721 KIT proto-oncogene, receptor tyrosine kinase Kinase 0.98 0.366 0.808
RARB P10826 retinoic acid receptor beta Nuclear receptor 1.00 0.478 0.846
ERG P11308 ETS transcription factor ERG Transcription factor 0.96 0.453 0.808
PIM1 P11309 Pim-1 proto-oncogene, serine/threonine kinase Kinase 0.85 0.482 0.769
IGF2R P11717 insulin like growth factor 2 receptor Receptor 1.00 0.518 0.731
IL2RB P14784 interleukin 2 receptor subunit beta Receptor 0.29 0.491 0.846
FAH P16930 fumarylacetoacetate hydrolase 4.0E-17 0.612 0.538
TAL1 P17542 TAL bHLH transcription factor 1, erythroid differentiation factor Transcription factor 0.57 0.505 0.731
HK1 P19367 hexokinase 1 Kinase 0.91 0.542 0.731
HNF1A P20823 HNF1 homeobox A Nucleic acid binding 0.96 0.478 0.846
F2R P25116 coagulation factor II thrombin receptor G-protein coupled receptor 8.5E-03 0.444 0.846