Disease: Alzheimer disease, familial, type 3
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ABCA1 O95477 ATP binding cassette subfamily A member 1 Transporter 1.5E-13 0.467 0.846
ACHE P22303 acetylcholinesterase (Cartwright blood group) Enzyme 1.00 0.445 0.885
ADAM10 O14672 ADAM metallopeptidase domain 10 1.00 0.489 0.846
ADIPOQ Q15848 adiponectin, C1Q and collagen domain containing 4.6E-09 0.376 0.885
AGER Q15109 advanced glycosylation end-product specific receptor Receptor 6.4E-16 0.420 0.885
AKR1C4 P17516 aldo-keto reductase family 1 member C4 Enzyme 2.2E-17 0.587 0.846
ALB P02768 albumin Transporter 0.64 0.317 0.962
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962
APP P05067 amyloid beta precursor protein Enzyme modulator 4.7E-02 0.422 0.846
BACE1 P56817 beta-secretase 1 Enzyme 0.88 0.559 0.769
BCHE P06276 butyrylcholinesterase 1.1E-13 0.447 0.923
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923
CASP3 P42574 caspase 3 Enzyme 0.10 0.351 0.923
CD36 P16671 CD36 molecule Receptor 1.1E-60 0.446 0.846
CDR1 P51861 cerebellar degeneration related protein 1 0.576 0.808
CHAT P28329 choline O-acetyltransferase Enzyme 5.6E-11 0.520 0.808
CHI3L1 P36222 chitinase 3 like 1 1.1E-05 0.419 0.885
CLU P10909 clusterin 7.8E-05 0.426 0.885
COL11A2 P13942 collagen type XI alpha 2 chain 0.70 0.435 0.846
CRP P02741 C-reactive protein 3.7E-03 0.299 0.962
CSF2 P04141 colony stimulating factor 2 Signaling 0.83 0.330 0.962
CX3CL1 P78423 C-X3-C motif chemokine ligand 1 Signaling 0.61 0.478 0.808
DKK1 O94907 dickkopf WNT signaling pathway inhibitor 1 0.17 0.439 0.885
DRD2 P14416 dopamine receptor D2 G-protein coupled receptor 0.75 0.436 0.846