Disease: Steroid Sulfatase Deficiency Disease
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
PEBP1 P30086 phosphatidylethanolamine binding protein 1 Enzyme modulator 9.2E-02 0.500 0.808
MITF O75030 melanocyte inducing transcription factor 0.98 0.499 0.808
TOP2A P11388 DNA topoisomerase II alpha 0.99 0.497 0.731
CA9 Q16790 carbonic anhydrase 9 1.3E-09 0.483 0.731
CD47 Q08722 CD47 molecule 0.92 0.468 0.769
EPAS1 Q99814 endothelial PAS domain protein 1 Transcription factor 0.60 0.454 0.731
HSPB1 P04792 heat shock protein family B (small) member 1 2.8E-07 0.436 0.808
SETD2 Q9BYW2 SET domain containing 2, histone lysine methyltransferase Epigenetic regulator 1.00 0.424 0.846
RASSF1 Q9NS23 Ras association domain family member 1 Enzyme modulator 4.9E-06 0.420 0.808
TNFSF10 P50591 TNF superfamily member 10 Signaling 0.13 0.413 0.885
ALK Q9UM73 ALK receptor tyrosine kinase Kinase 3.2E-06 0.396 0.846
MUC1 P15941 mucin 1, cell surface associated 1.9E-02 0.384 0.885
TIMP1 P01033 TIMP metallopeptidase inhibitor 1 Enzyme modulator 0.50 0.380 0.885
KDR P35968 kinase insert domain receptor Kinase 1.00 0.378 0.885
KIT P10721 KIT proto-oncogene, receptor tyrosine kinase Kinase 0.98 0.366 0.808
EGF P01133 epidermal growth factor 8.5E-17 0.357 0.923
MYC P01106 MYC proto-oncogene, bHLH transcription factor Transcription factor 1.00 0.344 0.923
MTOR P42345 mechanistic target of rapamycin kinase Kinase 1.00 0.343 0.885
ERBB2 P04626 erb-b2 receptor tyrosine kinase 2 Kinase 6.0E-03 0.328 0.923
HIF1A Q16665 hypoxia inducible factor 1 subunit alpha Transcription factor 0.98 0.327 0.923
CD274 Q9NZQ7 CD274 molecule Receptor 1.9E-02 0.324 0.923
BRAF P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1.00 0.319 0.846
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885