Disease: Steroid Sulfatase Deficiency Disease
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
MITF O75030 melanocyte inducing transcription factor 0.98 0.499 0.808
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885
TIMP1 P01033 TIMP metallopeptidase inhibitor 1 Enzyme modulator 0.50 0.380 0.885
MYC P01106 MYC proto-oncogene, bHLH transcription factor Transcription factor 1.00 0.344 0.923
EGF P01133 epidermal growth factor 8.5E-17 0.357 0.923
ERBB2 P04626 erb-b2 receptor tyrosine kinase 2 Kinase 6.0E-03 0.328 0.923
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
HSPB1 P04792 heat shock protein family B (small) member 1 2.8E-07 0.436 0.808
IL6 P05231 interleukin 6 0.32 0.248 0.962
KIT P10721 KIT proto-oncogene, receptor tyrosine kinase Kinase 0.98 0.366 0.808
TOP2A P11388 DNA topoisomerase II alpha 0.99 0.497 0.731
BRAF P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1.00 0.319 0.846
VEGFA P15692 vascular endothelial growth factor A Signaling 2.4E-05 0.266 0.923
MUC1 P15941 mucin 1, cell surface associated 1.9E-02 0.384 0.885
PEBP1 P30086 phosphatidylethanolamine binding protein 1 Enzyme modulator 9.2E-02 0.500 0.808
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962
KDR P35968 kinase insert domain receptor Kinase 1.00 0.378 0.885
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
MTOR P42345 mechanistic target of rapamycin kinase Kinase 1.00 0.343 0.885
TNFSF10 P50591 TNF superfamily member 10 Signaling 0.13 0.413 0.885
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923
CD47 Q08722 CD47 molecule 0.92 0.468 0.769
HIF1A Q16665 hypoxia inducible factor 1 subunit alpha Transcription factor 0.98 0.327 0.923
CA9 Q16790 carbonic anhydrase 9 1.3E-09 0.483 0.731
EPAS1 Q99814 endothelial PAS domain protein 1 Transcription factor 0.60 0.454 0.731