Disease: Steroid Sulfatase Deficiency Disease
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ALK Q9UM73 ALK receptor tyrosine kinase Kinase 3.2E-06 0.396 0.846
CD274 Q9NZQ7 CD274 molecule Receptor 1.9E-02 0.324 0.923
RASSF1 Q9NS23 Ras association domain family member 1 Enzyme modulator 4.9E-06 0.420 0.808
SETD2 Q9BYW2 SET domain containing 2, histone lysine methyltransferase Epigenetic regulator 1.00 0.424 0.846
EPAS1 Q99814 endothelial PAS domain protein 1 Transcription factor 0.60 0.454 0.731
CA9 Q16790 carbonic anhydrase 9 1.3E-09 0.483 0.731
HIF1A Q16665 hypoxia inducible factor 1 subunit alpha Transcription factor 0.98 0.327 0.923
CD47 Q08722 CD47 molecule 0.92 0.468 0.769
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923
TNFSF10 P50591 TNF superfamily member 10 Signaling 0.13 0.413 0.885
MTOR P42345 mechanistic target of rapamycin kinase Kinase 1.00 0.343 0.885
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
KDR P35968 kinase insert domain receptor Kinase 1.00 0.378 0.885
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962
PEBP1 P30086 phosphatidylethanolamine binding protein 1 Enzyme modulator 9.2E-02 0.500 0.808
MUC1 P15941 mucin 1, cell surface associated 1.9E-02 0.384 0.885
VEGFA P15692 vascular endothelial growth factor A Signaling 2.4E-05 0.266 0.923
BRAF P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1.00 0.319 0.846
TOP2A P11388 DNA topoisomerase II alpha 0.99 0.497 0.731
KIT P10721 KIT proto-oncogene, receptor tyrosine kinase Kinase 0.98 0.366 0.808
IL6 P05231 interleukin 6 0.32 0.248 0.962
HSPB1 P04792 heat shock protein family B (small) member 1 2.8E-07 0.436 0.808
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
ERBB2 P04626 erb-b2 receptor tyrosine kinase 2 Kinase 6.0E-03 0.328 0.923
EGF P01133 epidermal growth factor 8.5E-17 0.357 0.923