Disease: Ichthyosis, X-Linked
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
TACC3 Q9Y6A5 transforming acidic coiled-coil containing protein 3 2.7E-07 0.615 0.615
GAB2 Q9UQC2 GRB2 associated binding protein 2 Receptor 0.98 0.563 0.692
TOP2A P11388 DNA topoisomerase II alpha 0.99 0.497 0.731
MLRL Myeloid leukemia-related gene (myeloid tumor suppressor) 0.564 0.769
MIB1 Q86YT6 mindbomb E3 ubiquitin protein ligase 1 Enzyme 3.4E-88 0.438 0.769
CDK1 P06493 cyclin dependent kinase 1 Kinase 0.99 0.482 0.808
KIT P10721 KIT proto-oncogene, receptor tyrosine kinase Kinase 0.98 0.366 0.808
MKI67 P46013 marker of proliferation Ki-67 1.3E-28 0.431 0.808
NME1 P15531 NME/NM23 nucleoside diphosphate kinase 1 Kinase 3.2E-03 0.443 0.808
NRAS P01111 NRAS proto-oncogene, GTPase Enzyme modulator 0.49 0.390 0.808
PDGFRA P16234 platelet derived growth factor receptor alpha Kinase 1.00 0.415 0.808
EZR P15311 ezrin Cellular structure 0.18 0.476 0.808
CHEK2 O96017 checkpoint kinase 2 Kinase 1.2E-24 0.460 0.808
MUC5B Q9HC84 mucin 5B, oligomeric mucus/gel-forming 1.00 0.532 0.808
ALK Q9UM73 ALK receptor tyrosine kinase Kinase 3.2E-06 0.396 0.846
BRAF P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1.00 0.319 0.846
BRCA2 P51587 BRCA2 DNA repair associated Nucleic acid binding 2.4E-25 0.379 0.846
TIMM8A O60220 translocase of inner mitochondrial membrane 8A 0.65 0.510 0.846
MDM2 Q00987 MDM2 proto-oncogene Nucleic acid binding 1.00 0.362 0.846
RARA P10276 retinoic acid receptor alpha Nuclear receptor 0.96 0.470 0.846
TYMS P04818 thymidylate synthetase Enzyme 0.72 0.425 0.846
FOXP3 Q9BZS1 forkhead box P3 0.99 0.368 0.846
KRT20 P35900 keratin 20 9.1E-11 0.388 0.846
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885
CDKN2A P42771 Q8N726 cyclin dependent kinase inhibitor 2A 0.39 0.300 0.885