Disease: Hereditary Nonpolyposis Colorectal Cancer
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ST8 suppression of tumorigenicity 8 (ovarian) 0.780 0.269
CTNNA1 P35221 catenin alpha 1 Cellular structure 0.97 0.584 0.538
RNF43 Q68DV7 ring finger protein 43 0.73 0.584 0.577
PTPRG P23470 protein tyrosine phosphatase receptor type G Enzyme 5.1E-06 0.619 0.731
SPRR2A P35326 small proline rich protein 2A 0.612 0.731
CDKN1B P46527 cyclin dependent kinase inhibitor 1B 0.62 0.409 0.769
CDX2 Q99626 caudal type homeobox 2 Transcription factor 0.53 0.458 0.769
MUTYH Q9UIF7 mutY DNA glycosylase Enzyme 1.3E-18 0.521 0.769
PALB2 Q86YC2 partner and localizer of BRCA2 3.0E-19 0.485 0.769
CDH1 P12830 cadherin 1 0.15 0.401 0.808
SMAD4 Q13485 SMAD family member 4 Transcription factor 1.00 0.401 0.808
MLH1 P40692 mutL homolog 1 Nucleic acid binding 3.4E-05 0.399 0.808
CHEK2 O96017 checkpoint kinase 2 Kinase 1.2E-24 0.460 0.808
GREM1 O60565 gremlin 1, DAN family BMP antagonist 0.47 0.508 0.808
APEX1 P27695 apurinic/apyrimidinic endodeoxyribonuclease 1 1.9E-07 0.458 0.846
BRCA2 P51587 BRCA2 DNA repair associated Nucleic acid binding 2.4E-25 0.379 0.846
KLF6 Q99612 Kruppel like factor 6 Nucleic acid binding 0.98 0.501 0.846
DNMT3B Q9UBC3 DNA methyltransferase 3 beta 0.20 0.453 0.846
ERCC2 P18074 ERCC excision repair 2, TFIIH core complex helicase subunit Enzyme 7.1E-20 0.420 0.846
MRC1 P22897 mannose receptor C-type 1 0.94 0.413 0.846
TGFBR2 P37173 transforming growth factor beta receptor 2 Kinase 0.13 0.413 0.846
ARID1A O14497 AT-rich interaction domain 1A 1.00 0.455 0.846
ATM Q13315 ATM serine/threonine kinase Kinase 5.6E-47 0.374 0.885
CDKN2A P42771 Q8N726 cyclin dependent kinase inhibitor 2A 0.39 0.300 0.885
CTNNB1 P35222 catenin beta 1 1.00 0.303 0.885