Disease: Hereditary Nonpolyposis Colorectal Cancer
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ST8 suppression of tumorigenicity 8 (ovarian) 0.780 0.269
ARID1A O14497 AT-rich interaction domain 1A 1.00 0.455 0.846
GREM1 O60565 gremlin 1, DAN family BMP antagonist 0.47 0.508 0.808
CHEK2 O96017 checkpoint kinase 2 Kinase 1.2E-24 0.460 0.808
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885
SERPINA1 P01009 serpin family A member 1 Enzyme modulator 6.8E-08 0.410 0.923
MYC P01106 MYC proto-oncogene, bHLH transcription factor Transcription factor 1.00 0.344 0.923
HRAS P01112 HRas proto-oncogene, GTPase Enzyme modulator 8.0E-02 0.378 0.885
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923
ERBB2 P04626 erb-b2 receptor tyrosine kinase 2 Kinase 6.0E-03 0.328 0.923
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
GSTP1 P09211 glutathione S-transferase pi 1 1.4E-02 0.383 0.923
MMP7 P09237 matrix metallopeptidase 7 Enzyme 1.0E-09 0.446 0.885
CDH1 P12830 cadherin 1 0.15 0.401 0.808
CD44 P16070 CD44 molecule (Indian blood group) 2.4E-07 0.363 0.962
ERCC2 P18074 ERCC excision repair 2, TFIIH core complex helicase subunit Enzyme 7.1E-20 0.420 0.846
MRC1 P22897 mannose receptor C-type 1 0.94 0.413 0.846
PTPRG P23470 protein tyrosine phosphatase receptor type G Enzyme 5.1E-06 0.619 0.731
CCND1 P24385 cyclin D1 Enzyme modulator 0.89 0.344 0.923
APC P25054 APC regulator of WNT signaling pathway 1.00 0.373 0.962
APEX1 P27695 apurinic/apyrimidinic endodeoxyribonuclease 1 1.9E-07 0.458 0.846
CTNNA1 P35221 catenin alpha 1 Cellular structure 0.97 0.584 0.538
CTNNB1 P35222 catenin beta 1 1.00 0.303 0.885
SPRR2A P35326 small proline rich protein 2A 0.612 0.731
PTGS2 P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1.00 0.314 0.962