Disease: Mixed anxiety and depressive disorder
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923
COMT P21964 catechol-O-methyltransferase Enzyme 1.1E-06 0.400 0.923
CRHR1 P34998 corticotropin releasing hormone receptor 1 3.8E-05 0.517 0.769
CRP P02741 C-reactive protein 3.7E-03 0.299 0.962
DRD2 P14416 dopamine receptor D2 G-protein coupled receptor 0.75 0.436 0.846
DRD3 P35462 dopamine receptor D3 G-protein coupled receptor 2.4E-03 0.529 0.692
DRD4 P21917 dopamine receptor D4 G-protein coupled receptor 9.3E-09 0.517 0.577
DTNBP1 Q96EV8 dystrobrevin binding protein 1 6.8E-06 0.588 0.615
GAD2 Q05329 glutamate decarboxylase 2 Enzyme 0.75 0.529 0.731
HSD11B1 P28845 hydroxysteroid 11-beta dehydrogenase 1 0.42 0.520 0.731
HTR1A P08908 5-hydroxytryptamine receptor 1A G-protein coupled receptor 0.20 0.522 0.846
IL6 P05231 interleukin 6 0.32 0.248 0.962
KRT7 P08729 keratin 7 3.1E-12 0.463 0.808
L1CAM P32004 L1 cell adhesion molecule 1.00 0.475 0.769
MAOA P21397 monoamine oxidase A 1.00 0.465 0.769
MCIDAS D6RGH6 multiciliate differentiation and DNA synthesis associated cell cycle protein 1.3E-02 0.566 0.769
MTHFR P42898 methylenetetrahydrofolate reductase 3.2E-10 0.337 0.885
NOS1 P29475 nitric oxide synthase 1 1.00 0.408 0.885
NPY P01303 neuropeptide Y Signaling 0.14 0.447 0.846
OPRM1 P35372 opioid receptor mu 1 G-protein coupled receptor 7.9E-11 0.457 0.808
OXTR P30559 oxytocin receptor G-protein coupled receptor 7.1E-04 0.541 0.769
P2RX7 Q99572 purinergic receptor P2X 7 Ion channel 3.3E-11 0.450 0.808
PSS Potocki-Shaffer syndrome 0.608 0.654
SCLY Q96I15 selenocysteine lyase Enzyme 2.3E-09 0.530 0.731