Disease: Childhood Pilocytic Astrocytoma
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
MIB1 Q86YT6 mindbomb E3 ubiquitin protein ligase 1 Enzyme 3.4E-88 0.438 0.769
MKI67 P46013 marker of proliferation Ki-67 1.3E-28 0.431 0.808
PROM1 O43490 prominin 1 Transporter 1.9E-22 0.410 0.846
GADL1 Q6ZQY3 glutamate decarboxylase like 1 1.4E-21 0.497 0.808
IDH1 O75874 isocitrate dehydrogenase (NADP(+)) 1 2.6E-12 0.424 0.808
AZIN2 Q96A70 antizyme inhibitor 2 Enzyme 8.9E-07 0.499 0.808
PIK3CG P48736 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma Kinase 1.4E-06 0.320 0.885
GFAP P14136 glial fibrillary acidic protein 1.5E-06 0.421 0.885
ABCB1 P08183 ATP binding cassette subfamily B member 1 Transporter 1.3E-05 0.344 0.885
FGFR3 P22607 fibroblast growth factor receptor 3 Kinase 1.6E-05 0.391 0.846
VEGFA P15692 vascular endothelial growth factor A Signaling 2.4E-05 0.266 0.923
S100A1 P23297 S100 calcium binding protein A1 Calcium-binding protein 6.0E-03 0.421 0.846
S100B P04271 S100 calcium binding protein B Calcium-binding protein 4.4E-02 0.383 0.923
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923
DCX O43602 doublecortin 0.30 0.511 0.769
SST P61278 somatostatin Signaling 0.34 0.399 0.885
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885
CDKN2A P42771 Q8N726 cyclin dependent kinase inhibitor 2A 0.39 0.300 0.885
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
ZEB1 P37275 zinc finger E-box binding homeobox 1 Transcription factor 0.97 0.442 0.808
KIT P10721 KIT proto-oncogene, receptor tyrosine kinase Kinase 0.98 0.366 0.808
SOX10 P56693 SRY-box transcription factor 10 0.99 0.461 0.808
SOX9 P48436 SRY-box transcription factor 9 1.00 0.419 0.846
ERBB4 Q15303 erb-b2 receptor tyrosine kinase 4 Kinase 1.00 0.455 0.846
PIK3CB P42338 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta Kinase 1.00 0.322 0.885