Disease: Childhood Pilocytic Astrocytoma
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
PIK3CD O00329 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta Kinase 1.00 0.319 0.885
PROM1 O43490 prominin 1 Transporter 1.9E-22 0.410 0.846
DCX O43602 doublecortin 0.30 0.511 0.769
IDH1 O75874 isocitrate dehydrogenase (NADP(+)) 1 2.6E-12 0.424 0.808
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885
S100B P04271 S100 calcium binding protein B Calcium-binding protein 4.4E-02 0.383 0.923
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
ABCB1 P08183 ATP binding cassette subfamily B member 1 Transporter 1.3E-05 0.344 0.885
KIT P10721 KIT proto-oncogene, receptor tyrosine kinase Kinase 0.98 0.366 0.808
FGFR1 P11362 fibroblast growth factor receptor 1 Kinase 1.00 0.362 0.885
GFAP P14136 glial fibrillary acidic protein 1.5E-06 0.421 0.885
VEGFA P15692 vascular endothelial growth factor A Signaling 2.4E-05 0.266 0.923
FGFR3 P22607 fibroblast growth factor receptor 3 Kinase 1.6E-05 0.391 0.846
S100A1 P23297 S100 calcium binding protein A1 Calcium-binding protein 6.0E-03 0.421 0.846
EPHB2 P29323 EPH receptor B2 Kinase 1.00 0.374 0.846
KDR P35968 kinase insert domain receptor Kinase 1.00 0.378 0.885
ZEB1 P37275 zinc finger E-box binding homeobox 1 Transcription factor 0.97 0.442 0.808
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
PIK3CB P42338 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta Kinase 1.00 0.322 0.885
CDKN2A P42771 Q8N726 cyclin dependent kinase inhibitor 2A 0.39 0.300 0.885
MKI67 P46013 marker of proliferation Ki-67 1.3E-28 0.431 0.808
ATRX P46100 ATRX chromatin remodeler 1.00 0.452 0.808
SOX9 P48436 SRY-box transcription factor 9 1.00 0.419 0.846
PIK3CG P48736 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma Kinase 1.4E-06 0.320 0.885
SOX10 P56693 SRY-box transcription factor 10 0.99 0.461 0.808