Disease: Ataxia
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923
FGFR1 P11362 fibroblast growth factor receptor 1 Kinase 1.00 0.362 0.885
BRCA1 P38398 BRCA1 DNA repair associated Enzyme 9.2E-29 0.367 0.923
APC P25054 APC regulator of WNT signaling pathway 1.00 0.373 0.962
ATM Q13315 ATM serine/threonine kinase Kinase 5.6E-47 0.374 0.885
SLC2A1 P11166 solute carrier family 2 member 1 Transporter 0.99 0.388 0.808
GJA1 P17302 gap junction protein alpha 1 Cell-cell junction 0.16 0.393 0.885
SOX2 P48431 SRY-box transcription factor 2 Transcription factor 0.71 0.405 0.808
DNMT1 P26358 DNA methyltransferase 1 Epigenetic regulator 1.00 0.406 0.885
ATN1 P54259 atrophin 1 1.00 0.409 0.885
SYT1 P21579 synaptotagmin 1 Transporter 0.60 0.412 0.846
ERCC2 P18074 ERCC excision repair 2, TFIIH core complex helicase subunit Enzyme 7.1E-20 0.420 0.846
XRCC1 P18887 X-ray repair cross complementing 1 6.3E-09 0.421 0.923
TTR P02766 transthyretin Transporter 0.52 0.423 0.885
SQSTM1 Q13501 sequestosome 1 8.6E-04 0.428 0.885
HSPD1 P10809 heat shock protein family D (Hsp60) member 1 0.99 0.432 0.808
SMARCB1 Q12824 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 Nucleic acid binding 1.00 0.434 0.846
SPG7 Q9UQ90 SPG7 matrix AAA peptidase subunit, paraplegin Enzyme 2.0E-36 0.436 0.885
PTPN22 Q9Y2R2 protein tyrosine phosphatase non-receptor type 22 3.5E-21 0.438 0.846
CHD7 Q9P2D1 chromodomain helicase DNA binding protein 7 1.00 0.441 0.846
VHL P40337 von Hippel-Lindau tumor suppressor Enzyme 8.0E-02 0.443 0.846
PRNP F7VJQ1 P04156 prion protein 6.3E-04 0.445 0.923
PRRT2 Q7Z6L0 proline rich transmembrane protein 2 0.58 0.448 0.808
COL18A1 P39060 collagen type XVIII alpha 1 chain 1.7E-10 0.449 0.808
PAX6 P26367 paired box 6 1.00 0.450 0.769