Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
CDKN2A P42771 Q8N726 cyclin dependent kinase inhibitor 2A 0.39 0.300 0.885
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923
H3P10 H3 histone pseudogene 10 0.350 0.846
BRCA1 P38398 BRCA1 DNA repair associated Enzyme 9.2E-29 0.367 0.923
ATM Q13315 ATM serine/threonine kinase Kinase 5.6E-47 0.374 0.885
BRCA2 P51587 BRCA2 DNA repair associated Nucleic acid binding 2.4E-25 0.379 0.846
TIMP1 P01033 TIMP metallopeptidase inhibitor 1 Enzyme modulator 0.50 0.380 0.885
SMAD4 Q13485 SMAD family member 4 Transcription factor 1.00 0.401 0.808
ERCC2 P18074 ERCC excision repair 2, TFIIH core complex helicase subunit Enzyme 7.1E-20 0.420 0.846
LCN2 P80188 lipocalin 2 Enzyme 1.1E-09 0.405 0.885
MSH2 P43246 mutS homolog 2 Nucleic acid binding 0.90 0.406 0.808
CDKN1A P38936 cyclin dependent kinase inhibitor 1A 1.9E-03 0.403 0.769
CFTR P13569 CF transmembrane conductance regulator Ion channel 2.2E-58 0.424 0.885
STK11 Q15831 serine/threonine kinase 11 Kinase 0.99 0.435 0.808
S100A9 P06702 S100 calcium binding protein A9 Calcium-binding protein 0.48 0.433 0.885
CHEK2 O96017 checkpoint kinase 2 Kinase 1.2E-24 0.460 0.808
MSH6 P52701 mutS homolog 6 Nucleic acid binding 3.7E-05 0.462 0.731
CDK2 P24941 cyclin dependent kinase 2 Kinase 0.61 0.456 0.692
PALB2 Q86YC2 partner and localizer of BRCA2 3.0E-19 0.485 0.769
SUB1 P53999 SUB1 regulator of transcription 0.89 0.465 0.846
CD47 Q08722 CD47 molecule 0.92 0.468 0.769
FANCC Q00597 FA complementation group C 2.8E-13 0.507 0.808
SPINK1 P00995 serine peptidase inhibitor Kazal type 1 0.31 0.492 0.808
ALPP P05187 alkaline phosphatase, placental Enzyme 1.8E-13 0.487 0.808