Disease: Common Variable Immunodeficiency
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
FUT2 Q10981 fucosyltransferase 2 Enzyme 5.3E-14 0.552 0.731
CCR7 P32248 C-C motif chemokine receptor 7 G-protein coupled receptor 5.8E-02 0.443 0.769
GEM P55040 GTP binding protein overexpressed in skeletal muscle 1.2E-08 0.467 0.769
IGHG3 P01860 immunoglobulin heavy constant gamma 3 (G3m marker) 0.513 0.769
KIR2DS1 Q14954 killer cell immunoglobulin like receptor, two Ig domains and short cytoplasmic tail 1 Receptor 0.537 0.769
KIR3DL1 P43629 killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 1 Receptor 8.4E-14 0.475 0.769
KIR3DL2 P43630 killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 2 Receptor 6.1E-12 0.543 0.769
CCL21 O00585 C-C motif chemokine ligand 21 Signaling 3.6E-02 0.502 0.769
ATG16L1 Q676U5 autophagy related 16 like 1 0.96 0.543 0.769
IL21 Q9HBE4 interleukin 21 0.63 0.441 0.769
IL23R Q5VWK5 interleukin 23 receptor Signaling 5.6E-04 0.466 0.769
DAG1 Q14118 dystroglycan 1 Receptor 0.98 0.498 0.808
DPP4 P27487 dipeptidyl peptidase 4 Enzyme 7.3E-09 0.420 0.808
PTPRC P08575 protein tyrosine phosphatase receptor type C Enzyme 1.00 0.435 0.808
CDR3 Cerebellar degeneration-related autoantigen-3 0.472 0.808
LRRK2 Q5S007 leucine rich repeat kinase 2 Kinase 2.6E-30 0.510 0.808
AR P10275 androgen receptor Nuclear receptor 0.99 0.351 0.846
FCN2 Q15485 ficolin 2 Signaling 3.6E-11 0.517 0.846
GATA3 P23771 GATA binding protein 3 0.90 0.415 0.846
HFE Q30201 homeostatic iron regulator 2.6E-08 0.436 0.846
HLA-A P04439 major histocompatibility complex, class I, A 1.3E-03 0.370 0.846
HLA-C P10321 major histocompatibility complex, class I, C 1.6E-06 0.415 0.846
HLA-DQA1 P01909 major histocompatibility complex, class II, DQ alpha 1 Immune response 2.4E-02 0.416 0.846
ISG20 Q96AZ6 interferon stimulated exonuclease gene 20 2.9E-03 0.414 0.846
MBL2 P11226 mannose binding lectin 2 Receptor 2.7E-03 0.390 0.846