Disease: Midface retrusion
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
BRAF P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1.00 0.319 0.846
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923
LMNA P02545 lamin A/C 1.00 0.384 0.885
PTPN11 Q06124 protein tyrosine phosphatase non-receptor type 11 1.00 0.385 0.923
NRAS P01111 NRAS proto-oncogene, GTPase Enzyme modulator 0.49 0.390 0.808
FGFR3 P22607 fibroblast growth factor receptor 3 Kinase 1.6E-05 0.391 0.846
PTCH1 Q13635 patched 1 1.00 0.398 0.885
ELN P15502 elastin 2.1E-14 0.415 0.885
FBN1 P35555 fibrillin 1 Calcium-binding protein 1.00 0.417 0.846
RAF1 P04049 Raf-1 proto-oncogene, serine/threonine kinase Kinase 0.85 0.418 0.885
FLNA P21333 filamin A 1.00 0.419 0.846
COL1A1 P02452 collagen type I alpha 1 chain 1.00 0.430 0.808
TBX1 O43435 T-box transcription factor 1 Transcription factor 0.84 0.433 0.808
COL2A1 P02458 collagen type II alpha 1 chain 1.00 0.444 0.846
COL18A1 P39060 collagen type XVIII alpha 1 chain 1.7E-10 0.449 0.808
FLNB O75369 filamin B 6.1E-10 0.458 0.923
SLC6A8 P48029 solute carrier family 6 member 8 Transporter 1.00 0.476 0.846
MED12 Q93074 mediator complex subunit 12 Transcription factor 1.00 0.476 0.769
PIK3R1 P27986 phosphoinositide-3-kinase regulatory subunit 1 Kinase 1.00 0.477 0.885
HDAC4 P56524 histone deacetylase 4 Epigenetic regulator 1.00 0.484 0.885
SOS1 Q07889 SOS Ras/Rac guanine nucleotide exchange factor 1 Enzyme modulator 1.00 0.485 0.808
P4HB P07237 prolyl 4-hydroxylase subunit beta 1.00 0.488 0.808
RPS6KA3 P51812 ribosomal protein S6 kinase A3 Kinase 1.00 0.491 0.846
SOX11 P35716 SRY-box transcription factor 11 Transcription factor 0.86 0.494 0.808
COL11A1 P12107 collagen type XI alpha 1 chain 1.00 0.495 0.846