Disease: Midface retrusion
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
A2ML1 A8K2U0 alpha-2-macroglobulin like 1 Enzyme modulator 1.6E-34 0.590 0.692
MRAS O14807 muscle RAS oncogene homolog Enzyme modulator 0.92 0.590 0.731
TBX1 O43435 T-box transcription factor 1 Transcription factor 0.84 0.433 0.808
OBSL1 O75147 obscurin like cytoskeletal adaptor 1 1.0E-25 0.686 0.308
FLNB O75369 filamin B 6.1E-10 0.458 0.923
GMNN O75496 geminin DNA replication inhibitor 0.11 0.554 0.808
SEC24D O94855 SEC24 homolog D, COPII coat complex component Transporter 1.3E-07 0.663 0.577
NRAS P01111 NRAS proto-oncogene, GTPase Enzyme modulator 0.49 0.390 0.808
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923
COL1A1 P02452 collagen type I alpha 1 chain 1.00 0.430 0.808
COL2A1 P02458 collagen type II alpha 1 chain 1.00 0.444 0.846
LMNA P02545 lamin A/C 1.00 0.384 0.885
RAF1 P04049 Raf-1 proto-oncogene, serine/threonine kinase Kinase 0.85 0.418 0.885
P4HB P07237 prolyl 4-hydroxylase subunit beta 1.00 0.488 0.808
RRAS P10301 RAS related Enzyme modulator 4.7E-03 0.543 0.808
COL11A1 P12107 collagen type XI alpha 1 chain 1.00 0.495 0.846
SKI P12755 SKI proto-oncogene 1.00 0.503 0.808
BRAF P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1.00 0.319 0.846
ELN P15502 elastin 2.1E-14 0.415 0.885
FLNA P21333 filamin A 1.00 0.419 0.846
FGFR3 P22607 fibroblast growth factor receptor 3 Kinase 1.6E-05 0.391 0.846
PIK3R1 P27986 phosphoinositide-3-kinase regulatory subunit 1 Kinase 1.00 0.477 0.885
PYCR1 P32322 pyrroline-5-carboxylate reductase 1 2.0E-04 0.570 0.654
FBN1 P35555 fibrillin 1 Calcium-binding protein 1.00 0.417 0.846
SOX11 P35716 SRY-box transcription factor 11 Transcription factor 0.86 0.494 0.808